Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 10/20 | 0.42 |
| ▸ | NPC1 | O15118 | 9/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | GLA | P06280 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | RUNX1 | Q01196 | 2/20 | 0.37 |
| ▸ | CBFB | Q13951 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 3/20 | 0.36 |
| ▸ | TOP1 | P11387 | 2/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2705690 | 0.81 | PDK1 (0.58) | PDK1POLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL23862103 | 0.76 | POLB (0.53) | PDK1POLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL22488059 | 0.76 | POLB (0.53) | PDK1POLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL28604628 | 0.75 | PDK1 (0.58) | PDK1POLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL20312936 | 0.74 | POLB (0.50) | PDK1POLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL30190003 | 0.72 | PDK1 (0.60) | PDK1POLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL140126 | 0.72 | PDK1 (0.60) | PDK1POLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL20312949 | 0.72 | NPC1 (0.53) | PDK1POLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL13310867 | 0.71 | PDK1 (0.58) | PDK1POLBRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL137507 | 0.71 | PDK1 (0.58) | PDK1POLBRAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2739624-A1 | FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL | Sumitomo Chemical Company, Limited (JP) | 2014-06-11 | — | — | EP | disclosed |
| WO-2013018928-A1 | FUSED HETEROCYCLIC COMPOUND AND USE THEREOF FOR PEST CONTROL | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-02-07 | — | — | WO | disclosed |
| WO-2011043404-A1 | HETEROCYCLIC COMPOUND AND ITS USE FOR CONTROL OF AN ARTHROPOD PEST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-04-14 | — | — | WO | disclosed |
| US-5683996-A | ISOCEPHALOSPORINS; GRAMPOSITIVE BACTERIA ESPECIALLY PENICILLIN-RESISTANT STAPHYLOCOCCUS; GRAMNEGATIVE BACTERIA, PARTICULARLY COLIFORM | ROUSSEL UCLAF (FR) | 1997-11-04 | — | — | US | disclosed |
| US-5385897-A | 3-(3-quaternary ammonium prop-1-enyl), 7-((2-(aminothiazol-4-yl), 2-(alkoxyimino)acetamido)-3-isocephems; penicillin-resistant staphylococcus | ROUSSEL-UCLAF (FR) | 1995-01-31 | — | — | US | disclosed |