Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 14/20 | 0.47 |
| ▸ | KDM5A | P29375 | 13/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 9/20 | 0.47 |
| ▸ | KDM4A | O75164 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18248869 | 0.84 | NUDT1 (0.45) | KDM5BKDM5AKDM4CKDM4A | |
| SCHEMBL1667425 | 0.82 | KDM5A (0.44) | KDM5A | |
| SCHEMBL1667426 | 0.81 | KDM5A (0.48) | KDM5BKDM5AKDM4CKDM4A | |
| SCHEMBL8235212 | 0.76 | PBK (0.62) | KDM5BKDM5AKDM4CKDM4A | |
| SCHEMBL18249045 | 0.75 | KDM4E (0.44) | KDM5BKDM5AKDM4CKDM4A | |
| SCHEMBL29893885 | 0.75 | DHODH (0.44) | KDM5BKDM5AKDM4C | |
| SCHEMBL6305824 | 0.74 | AURKA (0.58) | — | |
| SCHEMBL31569363 | 0.72 | AURKA (0.47) | KDM5BKDM5AKDM4CCYP19A1 | |
| SCHEMBL5693339 | 0.72 | PARP1 (0.46) | KDM5BKDM5AKDM4CKDM4A | |
| SCHEMBL18249050 | 0.72 | PBK (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891042-B1 | 2-OXO-1-PYRROLIDINE DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR THERAPEUTIC USE ON THE CENTRAL NERVOUS SYSTEM | UCB PHARMA SA (BE) | 2013-10-02 | — | — | EP | disclosed |
| EP-2308867-A2 | 2-oxo-1-pyrrolidine deriatives, processes for preparing them and their uses | UCB Pharma S.A. (BE) | 2011-04-13 | — | — | EP | disclosed |
| EP-2308870-A2 | 2-oxo-1-pyrrolidine deriatives, processes for preparing them and their uses | UCB Pharma S.A. (BE) | 2011-04-13 | — | — | EP | disclosed |