Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16632887 | 0.92 | RORC (0.74) | RORC | |
| SCHEMBL16633132 | 0.83 | RORC (0.66) | RORC | |
| SCHEMBL16639493 | 0.83 | RORC (0.75) | RORC | |
| SCHEMBL16639573 | 0.83 | RORC (0.62) | RORC | |
| SCHEMBL16632941 | 0.81 | RORC (0.84) | RORC | |
| SCHEMBL16632669 | 0.80 | RORC (0.74) | RORC | |
| SCHEMBL16632939 | 0.79 | RORC (0.81) | RORC | |
| SCHEMBL16639520 | 0.78 | RORC (0.79) | RORC | |
| SCHEMBL16632871 | 0.78 | RORC (0.82) | RORC | |
| SCHEMBL16632819 | 0.78 | RORC (1.00) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057951-A1 | METHYLENE LINKED QUINOLINYL MODULATORS OF ROR-GAMMA-T | Janssen Pharmaceutica N.V. (BE) | 2016-08-24 | — | — | EP | disclosed |
| WO-2015057205-A1 | METHYLENE LINKED QUINOLINYL MODULATORS OF ROR-GAMMA-T | JANSSEN PHARMACEUTICA NV (BE) | 2015-04-23 | — | — | WO | disclosed |