Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16639551 | 0.82 | RORC (0.81) | RORC | |
| SCHEMBL21518210 | 0.82 | RORC (0.53) | RORC | |
| SCHEMBL16633155 | 0.80 | RORC (0.71) | RORC | |
| SCHEMBL16632515 | 0.80 | RORC (0.58) | RORC | |
| SCHEMBL16633131 | 0.80 | RORC (0.85) | RORC | |
| SCHEMBL16633159 | 0.79 | RORC (0.72) | RORC | |
| SCHEMBL16632681 | 0.79 | RORC (0.78) | RORC | |
| SCHEMBL19327641 | 0.78 | RORC (0.90) | RORC | |
| SCHEMBL16460369 | 0.78 | RORC (0.57) | RORC | |
| SCHEMBL15648101 | 0.78 | RORC (0.61) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057951-A1 | METHYLENE LINKED QUINOLINYL MODULATORS OF ROR-GAMMA-T | Janssen Pharmaceutica N.V. (BE) | 2016-08-24 | — | — | EP | disclosed |
| WO-2015057205-A1 | METHYLENE LINKED QUINOLINYL MODULATORS OF ROR-GAMMA-T | JANSSEN PHARMACEUTICA NV (BE) | 2015-04-23 | — | — | WO | disclosed |