Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 14/20 | 0.70 |
| ▸ | BTK | Q06187 | 13/20 | 0.70 |
| ▸ | USP2 | O75604 | 4/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16655530 | 0.82 | PIK3CD (1.00) | PIK3CDBTKATR | |
| SCHEMBL16656011 | 0.78 | PIK3CD (0.59) | PIK3CDBTKATR | |
| SCHEMBL16655325 | 0.77 | PIK3CD (1.00) | PIK3CDBTKATR | |
| SCHEMBL16655337 | 0.71 | PIK3CD (0.75) | PIK3CDBTKATR | |
| SCHEMBL16655617 | 0.71 | ATR (0.47) | PIK3CDBTKATR | |
| SCHEMBL23908620 | 0.69 | PIK3CD (0.77) | PIK3CDBTKATR | |
| SCHEMBL16655515 | 0.69 | PIK3CD (0.68) | PIK3CDBTK | |
| SCHEMBL16655272 | 0.68 | PIK3CD (1.00) | PIK3CDBTKATR | |
| SCHEMBL3610794 | 0.67 | PIK3CD (0.75) | PIK3CDBTK | |
| SCHEMBL16655153 | 0.67 | PIK3CD (0.76) | PIK3CDBTKATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057970-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | Medivation Technologies, Inc. (US) | 2016-08-24 | — | — | EP | claimed |
| WO-2015058084-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECHNOLOGIES, INC. (US) | 2015-04-23 | — | — | WO | claimed |