Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 9/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 12/20 | 0.42 |
| ▸ | BTK | Q06187 | 11/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16655267 | 0.78 | ATR (0.76) | ATRPIK3CDBTK | |
| SCHEMBL16656011 | 0.75 | PIK3CD (0.59) | ATRPIK3CDBTK | |
| SCHEMBL16655920 | 0.71 | PIK3CD (0.70) | ATRPIK3CDBTK | |
| SCHEMBL5083828 | 0.66 | IGF1R (0.51) | PIK3CD | |
| SCHEMBL21387779 | 0.66 | QPCT (0.38) | BTK | |
| SCHEMBL16655575 | 0.66 | PIK3CD (0.66) | ATRPIK3CDBTK | |
| SCHEMBL16655264 | 0.66 | PIK3CD (0.69) | ATRPIK3CDBTK | |
| SCHEMBL16655349 | 0.66 | ATR (0.89) | ATRPIK3CDBTK | |
| SCHEMBL23123086 | 0.65 | QPCT (0.51) | — | |
| SCHEMBL16655710 | 0.65 | ATR (0.78) | ATRPIK3CDBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057970-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | Medivation Technologies, Inc. (US) | 2016-08-24 | — | — | EP | claimed |
| WO-2015058084-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECHNOLOGIES, INC. (US) | 2015-04-23 | — | — | WO | claimed |