Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16650478 | 0.90 | RORC (0.84) | RORC | |
| SCHEMBL16632101 | 0.82 | RORC (0.84) | RORC | |
| SCHEMBL16662059 | 0.81 | RORC (0.91) | RORC | |
| SCHEMBL16651799 | 0.81 | RORC (1.00) | RORC | |
| SCHEMBL16662491 | 0.80 | RORC (0.68) | RORC | |
| SCHEMBL16655819 | 0.79 | RORC (0.67) | RORC | |
| SCHEMBL16651926 | 0.78 | RORC (0.82) | RORC | |
| SCHEMBL16651707 | 0.78 | RORC (0.80) | RORC | |
| SCHEMBL21004630 | 0.78 | RORC (0.80) | RORC | |
| SCHEMBL16651480 | 0.78 | RORC (1.00) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057422-A1 | QUINOLINYL MODULATORS OF ROR(GAMMA)T | Janssen Pharmaceutica NV (BE) | 2016-08-24 | — | — | EP | disclosed |
| WO-2015057626-A1 | QUINOLINYL MODULATORS OF RORyT | JANSSEN PHARMACEUTICA NV (BE) | 2015-04-23 | — | — | WO | disclosed |