Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 18/20 | 0.49 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.49 |
| ▸ | ATR | Q13535 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | TEK | Q02763 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23908597 | 0.90 | BTK (0.61) | BTKPIK3CDATREGFRLCK | |
| SCHEMBL16655959 | 0.84 | BTK (0.68) | BTKPIK3CDATREGFRLCK | |
| SCHEMBL16655625 | 0.80 | PIK3CD (0.61) | BTKPIK3CDATREGFR | |
| SCHEMBL16665786 | 0.80 | PIK3CD (0.61) | BTKPIK3CDATREGFR | |
| SCHEMBL16655939 | 0.78 | PIK3CD (0.69) | BTKPIK3CDATREGFRLCK | |
| SCHEMBL16655759 | 0.76 | BTK (0.62) | BTKPIK3CDATREGFRLCK | |
| SCHEMBL16655479 | 0.74 | PIK3CD (0.68) | BTKPIK3CDATREGFRLCK | |
| SCHEMBL16656048 | 0.74 | PIK3CD (0.75) | BTKPIK3CDATREGFRSRC | |
| SCHEMBL16665687 | 0.74 | PIK3CD (0.75) | BTKPIK3CDATREGFRSRC | |
| SCHEMBL16655658 | 0.73 | ATR (0.71) | BTKPIK3CDATRLCKSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057970-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | Medivation Technologies, Inc. (US) | 2016-08-24 | — | — | EP | claimed |
| WO-2015058084-A1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECHNOLOGIES, INC. (US) | 2015-04-23 | — | — | WO | claimed |