SCHEMBL16656160

SCHEMBL16656160

CN1C(=O)c2ccc3c4c(ccc(c24)C1=O)C(=O)N(c1ccccc1)C3=O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.54
KMT2A Q03164 5/20 0.54
KDM4E B2RXH2 5/20 0.54
USP2 O75604 4/20 0.54
MAPT P10636 3/20 0.54
HTT P42858 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
KEAP1 Q14145 2/20 0.54
NFE2L2 Q16236 2/20 0.54
MEN1 O00255 4/20 0.54
POLB P06746 4/20 0.53
APAF1 O14727 1/20 0.53
ESR1 P03372 1/20 0.51
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51
RECQL P46063 2/20 0.51
TDP1 Q9NUW8 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
APOBEC3A P31941 1/20 0.51
CASP6 P55212 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31167971 0.90 POLB (0.63) ALDH1A1KMT2AKDM4EUSP2MAPT
SCHEMBL7491321 0.90 POLB (0.63) ALDH1A1KMT2AKDM4EUSP2MAPT
SCHEMBL14369577 0.83 ALDH1A1 (0.53) ALDH1A1KMT2AKDM4EUSP2MAPT
SCHEMBL13533868 0.83 ALDH1A1 (0.62) ALDH1A1KMT2AKDM4EMAPTMEN1
SCHEMBL7602121 0.82 ALDH1A1 (0.60) ALDH1A1KMT2AKDM4EUSP2MAPT
SCHEMBL29726032 0.82 ALDH1A1 (0.60) ALDH1A1KMT2AKDM4EUSP2MAPT
SCHEMBL7597251 0.82 ALDH1A1 (0.60) ALDH1A1KMT2AKDM4EUSP2MAPT
SCHEMBL1127945 0.82 ALDH1A1 (0.60) ALDH1A1KMT2AKDM4EUSP2MAPT
SCHEMBL6851073 0.81 ALDH1A1 (0.50) ALDH1A1KMT2ASMN1; SMN2MEN1ESR1
SCHEMBL30937815 0.81 MEN1 (0.55) ALDH1A1KMT2AKDM4EUSP2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed
US-9012112-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-04-21 US disclosed