Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12195291 | 1.00 | KDM4E (0.56) | KDM4ESMN1; SMN2MAPK1NPC1NR2F2 | |
| SCHEMBL14312189 | 0.93 | KDM4E (0.50) | KDM4ESMN1; SMN2MAPK1NPC1NR2F2 | |
| SCHEMBL14312122 | 0.89 | KDM4E (0.46) | KDM4ESMN1; SMN2MAPK1NPC1NR2F2 | |
| SCHEMBL14477666 | 0.89 | KDM4E (0.46) | KDM4ESMN1; SMN2MAPK1NPC1NR2F2 | |
| SCHEMBL17152939 | 0.86 | ALDH1A1 (0.59) | KDM4ESMN1; SMN2MAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL17985967 | 0.86 | KCNJ1 (0.63) | SMN1; SMN2NPC1RAB9AKCNJ1HTT | |
| SCHEMBL17985879 | 0.86 | KCNJ1 (0.48) | KDM4ESMN1; SMN2MAPK1NPC1NR2F2 | |
| SCHEMBL19431626 | 0.85 | ALDH1A1 (0.42) | KDM4ESMN1; SMN2MAPK1NPC1NR2F2 | |
| SCHEMBL9883952 | 0.85 | ALDH1A1 (0.48) | KDM4ESMN1; SMN2MAPK1NPC1NR2F2 | |
| SCHEMBL377491 | 0.85 | ALDH1A1 (0.67) | KDM4ESMN1; SMN2MAPK1NPC1NR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012604-B2 | Triazanonane derivatives or pharmaceutically acceptable salt thereof for enhanced fluorine-18 labeling | Snur & DB Foundation (KR) | 2015-04-21 | — | — | US | disclosed |