Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 5/20 | 0.36 |
| ▸ | CASP1 | P29466 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | CASP7 | P55210 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 3/20 | 0.33 |
| ▸ | F11 | P03951 | 3/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1664819 | 0.84 | F2 (0.37) | ALDH1A1MAPTKDM4ESMN1; SMN2HPGD | |
| SCHEMBL1664597 | 0.78 | ALDH1A1 (0.43) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL1662907 | 0.77 | ALDH1A1 (0.48) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL1662993 | 0.77 | ALDH1A1 (0.47) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL1663371 | 0.77 | EGFR (0.43) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL1663125 | 0.73 | ALDH1A1 (0.40) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL515152 | 0.72 | ROCK1 (0.40) | F2F11PRSS1PRSS2PRSS3 | |
| SCHEMBL1664651 | 0.72 | ALDH1A1 (0.44) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL12795980 | 0.72 | HIF1A (0.31) | — | |
| SCHEMBL25380965 | 0.70 | KDM4E (0.38) | ALDH1A1MAPTKDM4ESMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |