Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAF1 | P04049 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13186255 | 0.86 | RAB9A (0.66) | SMN1; SMN2RAB9ANPC1TP53CNR1 | |
| SCHEMBL10213156 | 0.83 | KMT2A (0.56) | SMN1; SMN2RAB9ANPC1TP53CNR1 | |
| SCHEMBL12424047 | 0.66 | ABL1 (0.42) | SMN1; SMN2RAB9ANPC1TP53 | |
| SCHEMBL12424048 | 0.66 | MEN1 (0.43) | SMN1; SMN2RAB9ANPC1MAPTKMT2A | |
| SCHEMBL557468 | 0.66 | MAPT (0.45) | SMN1; SMN2RAB9ANPC1NPSR1MAPT | |
| SCHEMBL11651472 | 0.66 | RAB9A (1.00) | SMN1; SMN2RAB9ANPC1TP53NPSR1 | |
| SCHEMBL20557579 | 0.64 | CNR1 (1.00) | NPC1CNR1KMT2ALMNAMEN1 | |
| SCHEMBL30469274 | 0.64 | CNR1 (1.00) | NPC1CNR1KMT2ALMNAMEN1 | |
| SCHEMBL19626518 | 0.64 | KDM4E (0.53) | RAB9ANPC1MAPTKMT2AMEN1 | |
| SCHEMBL5944093 | 0.63 | PARP1 (0.69) | SMN1; SMN2RAB9ANPC1CNR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9012360-B2 | Synergistic combinations of active ingredients | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-04-21 | — | — | US | disclosed |