SCHEMBL16657338

SCHEMBL16657338

Cc1ccc(C2(c3ccc(-c4ccc(Br)cc4)cc3)c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
KDM4E B2RXH2 1/20 0.49
LMNA P02545 1/20 0.49
MAPT P10636 1/20 0.49
OPRK1 P41145 1/20 0.49
ESR1 P03372 1/20 0.45
ESR2 Q92731 1/20 0.45
ALDH1A1 P00352 2/20 0.43
PDK2 Q15119 4/20 0.43
MAPK1 P28482 2/20 0.41
SLC6A3 Q01959 1/20 0.40
KIF11 P52732 1/20 0.38
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
TSHR P16473 1/20 0.36
POLB P06746 1/20 0.35
MGAM O43451 1/20 0.35
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10047418 0.95 MEN1 (0.53) SMN1; SMN2MEN1KMT2AKDM4ELMNA
SCHEMBL17816645 0.93 MEN1 (0.52) SMN1; SMN2MEN1KMT2AKDM4ELMNA
SCHEMBL425474 0.89 MEN1 (0.51) SMN1; SMN2MEN1KMT2AKDM4ELMNA
SCHEMBL16852587 0.88 PDK2 (0.44) SMN1; SMN2MEN1KMT2AKDM4ELMNA
SCHEMBL31358608 0.88 SMN1; SMN2 (0.53) SMN1; SMN2MEN1KMT2AKDM4ELMNA
SCHEMBL1783501 0.88 SMN1; SMN2 (0.53) SMN1; SMN2MEN1KMT2AKDM4ELMNA
SCHEMBL15025999 0.86 MEN1 (0.45) SMN1; SMN2MEN1KMT2AKDM4ELMNA
SCHEMBL8984601 0.86 MEN1 (0.63) SMN1; SMN2MEN1KMT2AKDM4ELMNA
SCHEMBL30288909 0.86 MEN1 (0.63) SMN1; SMN2MEN1KMT2AKDM4ELMNA
SCHEMBL30009193 0.86 MEN1 (0.63) SMN1; SMN2MEN1KMT2AKDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9905774-B2 Organic electronic material GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD (CN) 2018-02-27 US disclosed
US-9905774-B2 Organic electronic material GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD (CN) 2018-02-27 US disclosed
US-9871202-B2 Organic electroluminescent device GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD (CN) 2018-01-16 US disclosed
US-9871202-B2 Organic electroluminescent device GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD (CN) 2018-01-16 US disclosed
US-20150144898-A1 ORGANIC ELECTROLUMINESCENT DEVICE GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD (CN) 2015-05-28 US disclosed
US-20150144898-A1 ORGANIC ELECTROLUMINESCENT DEVICE GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD (CN) 2015-05-28 US disclosed
US-20150108448-A1 ORGANIC ELECTRONIC MATERIAL GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD (CN) 2015-04-23 US disclosed
US-20150108448-A1 ORGANIC ELECTRONIC MATERIAL GUANGDONG AGLAIA OPTOELECTRONIC MATERIALS CO., LTD (CN) 2015-04-23 US disclosed