SCHEMBL1783501

SCHEMBL1783501

Brc1ccc(-c2ccc(C3(c4ccccc4)c4ccccc4-c4ccccc43)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
LMNA P02545 2/20 0.53
MAPT P10636 2/20 0.53
KDM4E B2RXH2 1/20 0.53
OPRK1 P41145 1/20 0.53
ALDH1A1 P00352 3/20 0.50
MAPK1 P28482 1/20 0.50
ESR1 P03372 1/20 0.41
ESR2 Q92731 1/20 0.41
POLB P06746 1/20 0.41
SLC6A3 Q01959 1/20 0.39
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
NFKB1 P19838 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
PDK2 Q15119 2/20 0.37
OPRM1 P35372 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31358608 1.00 SMN1; SMN2 (0.53) SMN1; SMN2MEN1KMT2ALMNAMAPT
SCHEMBL283196 0.94 MEN1 (0.59) SMN1; SMN2MEN1KMT2ALMNAMAPT
SCHEMBL29506706 0.94 MEN1 (0.59) SMN1; SMN2MEN1KMT2ALMNAMAPT
SCHEMBL17816646 0.92 MEN1 (0.57) SMN1; SMN2MEN1KMT2ALMNAMAPT
SCHEMBL12745130 0.91 MEN1 (0.45) SMN1; SMN2MEN1KMT2ALMNAMAPT
SCHEMBL28135141 0.90 MEN1 (0.63) SMN1; SMN2MEN1KMT2ALMNAMAPT
SCHEMBL30288909 0.90 MEN1 (0.63) SMN1; SMN2MEN1KMT2ALMNAMAPT
SCHEMBL105865 0.90 MEN1 (0.63) SMN1; SMN2MEN1KMT2ALMNAMAPT
SCHEMBL28680644 0.90 MEN1 (0.47) SMN1; SMN2MEN1KMT2ALMNAMAPT
SCHEMBL13312965 0.90 PDK2 (0.45) SMN1; SMN2MEN1KMT2ALMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11795182-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2023-10-24 US disclosed
US-11795182-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2023-10-24 US disclosed
US-11795182-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2023-10-24 US disclosed
US-11236114-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2022-02-01 US disclosed
CN-113698305-A Fluorene derivative, light-emitting element, light-emitting device, electronic device, and lighting device 株式会社半导体能源研究所 2021-11-26 CN disclosed
US-10862042-B2 Fluorene derivative, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-12-08 US disclosed
US-20200119276-A1 FLUORENE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-04-16 US disclosed
US-10553797-B2 Fluorene derivative, light-emitting elements, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2020-02-04 US disclosed
US-20190256529-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-08-22 US disclosed
US-10233199-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-03-19 US disclosed
US-8771840-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-07-08 US disclosed
EP-2330102-B1 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LAB (JP) 2012-07-18 EP disclosed
EP-2330102-A1 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device Semiconductor Energy Laboratory Co, Ltd. (JP) 2011-06-08 EP disclosed
US-20110114928-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2011-05-19 US disclosed
US-20110114928-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2011-05-19 US disclosed
US-20110114928-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2011-05-19 US disclosed
US-20100301744-A1 FLUORENE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-12-02 US disclosed
US-20100301744-A1 FLUORENE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-12-02 US disclosed
US-20100301744-A1 FLUORENE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-12-02 US disclosed
WO-2010137601-A1 FLUORENE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2010-12-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10233199-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device CRY1, CCNE2, CCNE1 SMN1; SMN2 4075/4885MEN1 210/4885KMT2A 2503/4885
US-20110114928-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device CRY1, CCNE2, CCNE1 SMN1; SMN2 4085/4885MEN1 220/4885KMT2A 2522/4885
US-11795182-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device CRY1, CCNE2, CCNE1 SMN1; SMN2 4085/4885MEN1 220/4885KMT2A 2522/4885
US-11236114-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device CRY1, CCNE2, CCNE1 SMN1; SMN2 4085/4885MEN1 220/4885KMT2A 2522/4885
US-20200119276-A1 FLUORENE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE NR2E3, AFF1, NR2E1 SMN1; SMN2 2606/4885MEN1 974/4885KMT2A 844/4885
US-10862042-B2 Fluorene derivative, light-emitting element, light-emitting device, electronic device, and lighting device NR2E3, AFF1, NR2E1 SMN1; SMN2 2606/4885MEN1 974/4885KMT2A 844/4885
US-10553797-B2 Fluorene derivative, light-emitting elements, light-emitting device, electronic device, and lighting device NR2E3, GRK1, AFF1 SMN1; SMN2 2515/4885MEN1 1088/4885KMT2A 731/4885
US-20100301744-A1 FLUORENE DERIVATIVE, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE NR2E3, NR2E1, AFF1 SMN1; SMN2 2547/4885MEN1 1141/4885KMT2A 753/4885
US-20190256529-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device CRY1, CCNE2, CCNE1 SMN1; SMN2 4085/4885MEN1 220/4885KMT2A 2522/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.