⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16821953 | 0.78 | SIGMAR1 (0.31) | — | |
| SCHEMBL3400008 | 0.75 | — | — | |
| SCHEMBL23878223 | 0.73 | — | — | |
| SCHEMBL2058389 | 0.73 | — | — | |
| SCHEMBL21620810 | 0.73 | — | — | |
| SCHEMBL27341141 | 0.73 | — | — | |
| SCHEMBL11073718 | 0.73 | — | — | |
| SCHEMBL8327572 | 0.73 | — | — | |
| SCHEMBL3608 | 0.72 | — | — | |
| SCHEMBL1695836 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9000107-B2 | Process for producing polydienes | BRIDGESTONE CORPORATION (JP) | 2015-04-07 | — | — | US | claimed |
| US-20120196995-A1 | PROCESS FOR PRODUCING POLYDIENES | BRIDGESTONE CORPORATION (JP) | 2012-08-02 | — | — | US | claimed |
| US-4087245-A | Process for the preparation of concentrated solutions of anionic dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-02 | — | — | US | claimed |
| EP-2753618-B1 | HETEROCYCLIC-SUBSTITUED BENZOFURAN DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES | MERCK SHARP & DOHME (US) | 2018-04-11 | — | — | EP | disclosed |
| US-9000107-B2 | Process for producing polydienes | BRIDGESTONE CORPORATION (JP) | 2015-04-07 | — | — | US | disclosed |
| US-8648072-B2 | Cannabinoid receptor antagonists/inverse agonists useful for treating metabolic disorders, including obesity and diabetes | JENRIN DISCOVERY, INC. (US) | 2014-02-11 | — | — | US | disclosed |
| US-20120264754-A1 | CANNABINOID RECEPTOR ANTAGONISTS/INVERSE AGONISTS USEFUL FOR TREATING METABOLIC DISORDERS, INCLUDING OBESITY AND DIABETES | JENRIN DISCOVERY (US) | 2012-10-18 | — | — | US | disclosed |
| US-20120196995-A1 | PROCESS FOR PRODUCING POLYDIENES | BRIDGESTONE CORPORATION (JP) | 2012-08-02 | — | — | US | disclosed |
| US-8217038-B2 | Cannabinoid receptor antagonists/inverse agonists useful for treating metabolic disorders, including obesity and diabetes | JENRIN DISCOVERY, INC. (US) | 2012-07-10 | — | — | US | disclosed |
| US-20110257178-A1 | CANNABINOID RECEPTOR ANTAGONISTS/INVERSE AGONISTS USEFUL FOR TREATING METABOLIC DISORDERS, INCLUDING OBESITY AND DIABETES | JENRIN DISCOVERY (US) | 2011-10-20 | — | — | US | disclosed |
| WO-2011044370-A1 | CANNABINOID RECEPTOR ANTAGONISTS/INVERSE AGONISTS USEFUL FOR TREATING METABOLIC DISORDERS, INCLUDING OBESITY AND DIABETES | JENRIN DISCOVERY (US) | 2011-04-14 | — | — | WO | disclosed |
| WO-2002050041-A1 | DIHYDROINDOLE AND TETRAHYDROQUINOLINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-06-27 | — | — | WO | disclosed |
| US-20020068753-A1 | 2,3-oxidosqualene-lanosterol cyclase inhibitors | HOFFMANN-LA ROCHE INC. | 2002-06-06 | — | — | US | disclosed |
| WO-2002036584-A1 | CHOLESTEROL LOWERING BENZO`B! THIOPHENES AND BENZO`D! ISOTHIAZOLES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-05-10 | — | — | WO | disclosed |
| WO-2002020483-A1 | PIPERIDINE DERIVATIVES FOR USE 2,3-OXIDOSQUALENE-LANOSTEROL CYCLASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2002-03-14 | — | — | WO | disclosed |
| WO-2000023444-A1 | 5,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-04-27 | — | — | WO | disclosed |
| CN-1037175-C | Halomethylbenzoyl cyanides and process for preparing same | BASF AG (DE) | 1998-01-28 | — | — | CN | disclosed |
| CN-1097412-A | Preparation of halomethylbenzoyl cyanides and novel halomethylbenzoyl cyanides | BASF AG (DE) | 1995-01-18 | — | — | CN | disclosed |
| US-4087245-A | Process for the preparation of concentrated solutions of anionic dyestuffs | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-02 | — | — | US | disclosed |
| US-4058517-A | Preparation of a concentrated solution of an anionic azo dye containing a sulfonic acid group | BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) | 1977-11-15 | — | — | US | disclosed |