SCHEMBL16659780

SCHEMBL16659780

C=C(C)C(=O)OCCOC(=O)c1ccc2cc(OC(C)C)ccc2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.46
APEX1 P27695 1/20 0.46
HTT P42858 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
KMT2A Q03164 1/20 0.41
MAPT P10636 2/20 0.40
TP53 P04637 1/20 0.40
HRH3 Q9Y5N1 2/20 0.40
PARP10 Q53GL7 1/20 0.40
ADRB2 P07550 1/20 0.39
ADRB1 P08588 1/20 0.39
ADRB3 P13945 1/20 0.39
DRD3 P35462 1/20 0.39
THRB P10828 1/20 0.38
F2 P00734 2/20 0.38
PLG P00747 2/20 0.38
PLAU P00749 2/20 0.38
PLAT P00750 2/20 0.38
KLKB1 P03952 2/20 0.38
PRSS1 P07477 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16659783 0.89 POLB (0.50) POLBAPEX1HTTTDP1KMT2A
SCHEMBL909434 0.88 POLB (0.47) POLBAPEX1HTTTDP1MAPT
SCHEMBL16661817 0.87 KDM4E (0.51) POLBAPEX1HTTTDP1KMT2A
SCHEMBL16659774 0.86 ADRB2 (0.50) POLBAPEX1HTTTDP1KMT2A
SCHEMBL14001889 0.85 POLB (0.48) POLBAPEX1HTTTDP1MAPT
SCHEMBL16243833 0.84 TDP1 (0.60) POLBAPEX1HTTTDP1HRH3
SCHEMBL26312599 0.84 HTT (0.47) POLBAPEX1HTTTDP1MAPT
SCHEMBL9880800 0.84 HRH3 (0.55) POLBAPEX1HTTTDP1KMT2A
SCHEMBL16659784 0.84 KMT2A (0.45) KMT2AMAPTTP53HRH3PARP10
SCHEMBL13609723 0.83 HRH3 (0.51) POLBAPEX1HTTTDP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9068082-B2 Colored curable composition and color filter FUJIFILM CORPORATION (JP) 2015-06-30 US disclosed
US-20150108086-A1 COLORED CURABLE COMPOSITION AND COLOR FILTER FUJIFILM CORPORATION (JP) 2015-04-23 US disclosed