Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP1 | P22413 | 6/20 | 0.67 |
| ▸ | ENPP3 | O14638 | 6/20 | 0.67 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.58 |
| ▸ | TUBB | P07437 | 2/20 | 0.58 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.58 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.58 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.58 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.58 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.58 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.58 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.58 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.58 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.58 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.58 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.58 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.58 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.58 |
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | CNR2 | P34972 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 8/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1665367 | 0.91 | ENPP1 (0.65) | ENPP1ENPP3TUBB4ATUBBTUBA3C | |
| SCHEMBL7148725 | 0.89 | CNR1 (0.70) | ENPP1ENPP3TUBB4ATUBBTUBA3C | |
| SCHEMBL1665215 | 0.85 | TUBB4A (0.65) | ENPP1ENPP3TUBB4ATUBBTUBA3C | |
| SCHEMBL5026252 | 0.84 | CNR1 (0.78) | ENPP1ENPP3TUBB4ATUBBTUBA3C | |
| SCHEMBL1665989 | 0.84 | CNR1 (0.61) | ENPP1ENPP3TUBB4ATUBBTUBA3C | |
| SCHEMBL19308141 | 0.83 | CNR1 (0.72) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL7120909 | 0.82 | TUBB4A (0.61) | ENPP1ENPP3TUBB4ATUBBTUBA3C | |
| SCHEMBL1665968 | 0.80 | CNR1 (0.67) | ENPP1ENPP3TUBB4ATUBBTUBA3C | |
| Potassium Ion SCHEMBL1666052 | 0.80 | CNR1 (0.67) | ENPP1ENPP3TUBB4ATUBBTUBA3C | |
| SCHEMBL1665792 | 0.80 | CNR1 (0.70) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2314581-B1 | A process for preparing benzo[b]thiophene derivatives | HEXAL AG (DE) | 2012-07-25 | — | — | EP | disclosed |
| EP-2322519-A1 | A process for preparing benzo[b]thiophene derivatives | Hexal AG (DE) | 2011-05-18 | — | — | EP | disclosed |
| WO-2011047878-A2 | A PROCESS FOR PREPARING BENZO[B]THIOPHENE DERIVATIVES | HEXAL AKTIENGESELLSCHAFT (DE) | 2011-04-28 | — | — | WO | disclosed |
| WO-2011047877-A1 | A PROCESS FOR PREPARING BENZO[B]THIOPHENE DERIVATIVES | HEXAL AKTIENGESELLSCHAFT (DE) | 2011-04-28 | — | — | WO | disclosed |
| EP-2314581-A1 | A process for preparing benzo[b]thiophene derivatives | Hexal AG (DE) | 2011-04-27 | — | — | EP | disclosed |