SCHEMBL16660347

SCHEMBL16660347

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nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ P2RY2 P41231 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17359476 0.92 P2RY2 (0.30) P2RY2
SCHEMBL18161325 0.91 P2RY2 (0.30) P2RY2
SCHEMBL16949606 0.91 RXFP1 (0.30) P2RY2
SCHEMBL15765744 0.91 P2RY2 (0.30) P2RY2
SCHEMBL15297346 0.91 P2RY2 (0.30) P2RY2
SCHEMBL15727323 0.90 — —
SCHEMBL15933540 0.90 — —
SCHEMBL19646631 0.87 P2RY2 (0.39) P2RY2
SCHEMBL18950205 0.85 P2RY14 (0.30) —
SCHEMBL14948854 0.85 P2RY2 (0.30) P2RY2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9221891-B2 In vivo production of proteins MODERNA THERAPEUTICS, INC. (US) 2015-12-29 — — US disclosed
US-20150111248-A1 IN VIVO PRODUCTION OF PROTEINS MODERNA THERAPEUTICS, INC. (US) 2015-04-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150111248-A1 IN VIVO PRODUCTION OF PROTEINS MSH2, POLRMT, POLN P2RY2 3346/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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