Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.50 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10079117 | 1.00 | HTR2C (0.50) | HTR2CP2RY14HTR2AGRM2DRD2 | |
| SCHEMBL13416025 | 0.90 | LSS (0.50) | HTR2CHTR2ADRD2PROKR1SLC6A2 | |
| SCHEMBL6884365 | 0.89 | HTR2C (0.58) | HTR2CP2RY14HTR2AGRM2DRD2 | |
| SCHEMBL24540179 | 0.86 | LSS (0.47) | HTR2CP2RY14HTR2APROKR1SIGMAR1 | |
| SCHEMBL15417384 | 0.84 | TP53 (0.43) | HTR2CHTR2ASIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL25594631 | 0.81 | DRD2 (0.41) | P2RY14HTR2ADRD2SLC6A2SLC6A4 | |
| SCHEMBL9230752 | 0.81 | DRD2 (0.64) | HTR2CGRM2DRD2DRD4 | |
| SCHEMBL13416053 | 0.80 | NPC1 (0.47) | HTR2CHTR2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL2606075 | 0.80 | NPC1 (0.47) | HTR2CHTR2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL25004303 | 0.80 | DRD2 (0.49) | HTR2CP2RY14GRM2DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2681215-B1 | SERINE/THREONINE KINASE INHIBITORS | ARRAY BIOPHARMA INC (US) | 2015-04-22 | — | — | EP | disclosed |