Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 13/20 | 0.66 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HNF4A | P41235 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | RARA | P10276 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | RARG | P13631 | 1/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27936863 | 0.89 | PDE4D (0.53) | PDE4DPTPN1MMP2MMP3MMP9 | |
| SCHEMBL16660604 | 0.82 | PDE4D (0.61) | PDE4DRARARARBRARGAKR1C2 | |
| SCHEMBL16660681 | 0.81 | PDE4D (0.85) | PDE4DPTPN1 | |
| SCHEMBL16660633 | 0.81 | PDE4D (0.84) | PDE4DPTPN1MMP2MMP3MMP9 | |
| SCHEMBL30832596 | 0.80 | PDE4D (1.00) | PDE4DPTPN1MMP2MMP3MMP9 | |
| SCHEMBL16660634 | 0.80 | PDE4D (1.00) | PDE4DPTPN1MMP2MMP3MMP9 | |
| SCHEMBL16660639 | 0.76 | PDE4D (0.82) | PDE4DCA12CA1CA2CA9 | |
| SCHEMBL27936845 | 0.71 | PDE4D (0.69) | PDE4DPTPN1MMP2MMP3MMP9 | |
| SCHEMBL31633741 | 0.69 | PDE4D (0.50) | PDE4DCA1CA2CA7CA9 | |
| SCHEMBL16660640 | 0.69 | PDE4D (1.00) | PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015055116-A1 | SELAGINELLA PULVINATA EXTRACTIVE AND PREPARATION METHOD AND APPLICATION THEREOF | 中山大学 | 2015-04-23 | — | — | WO | disclosed |