Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 13/20 | 1.00 |
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | P4HB | P07237 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | BCR | P11274 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16660639 | 0.91 | PDE4D (0.82) | PDE4DAPP | |
| SCHEMBL16660641 | 0.83 | PDE4D (0.71) | PDE4D | |
| SCHEMBL16660570 | 0.78 | PDE4D (0.64) | PDE4D | |
| SCHEMBL16660681 | 0.74 | PDE4D (0.85) | PDE4DAPP | |
| SCHEMBL27950604 | 0.72 | PDE4D (0.56) | PDE4DAPP | |
| SCHEMBL16660683 | 0.71 | PDE4D (0.84) | PDE4DAPPKCNH2 | |
| SCHEMBL29462973 | 0.71 | PDE4D (0.53) | PDE4DAPPLTA4HABL1ABCB1 | |
| SCHEMBL649109 | 0.71 | PDE4D (0.53) | PDE4DAPPLTA4HABL1ABCB1 | |
| SCHEMBL16660604 | 0.70 | PDE4D (0.61) | PDE4DAPP | |
| SCHEMBL30689253 | 0.70 | ESR2 (0.58) | PDE4DAPPLTA4HABL1ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103588616-B | A kind of Selaginella pulvinata extract and its preparation method and application | SUN YAT-SEN UNIVERSITY (CN) | 2015-09-09 | — | — | CN | disclosed |
| WO-2015055116-A1 | SELAGINELLA PULVINATA EXTRACTIVE AND PREPARATION METHOD AND APPLICATION THEREOF | 中山大学 | 2015-04-23 | — | — | WO | disclosed |
| CN-103588616-A | Selaginella pulvinata extract as well as preparation method and applications thereof | UNIV SUN YAT SEN | 2014-02-19 | — | — | CN | disclosed |