SCHEMBL649109

SCHEMBL649109

COc1ccc(C2(c3ccc(O)cc3)c3ccccc3-c3ccccc32)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE4D Q08499 8/20 0.53
ESR2 Q92731 2/20 0.49
ESR1 P03372 1/20 0.49
MAPT P10636 2/20 0.49
KMT2A Q03164 2/20 0.49
KDM4E B2RXH2 1/20 0.49
MEN1 O00255 1/20 0.49
LMNA P02545 1/20 0.49
OPRK1 P41145 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
LTA4H P09960 1/20 0.48
ABL1 P00519 1/20 0.46
ABCB1 P08183 1/20 0.46
BCR P11274 1/20 0.46
APP P05067 1/20 0.44
PDK2 Q15119 3/20 0.44
NPC1 O15118 1/20 0.43
MAPK1 P28482 1/20 0.43
RAB9A P51151 1/20 0.43
SLC6A3 Q01959 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29462973 1.00 PDE4D (0.53) PDE4DESR2ESR1MAPTKMT2A
SCHEMBL30873770 0.91 MAPT (0.57) PDE4DESR2ESR1MAPTKMT2A
SCHEMBL1702667 0.91 MAPT (0.57) PDE4DESR2ESR1MAPTKMT2A
SCHEMBL16905592 0.90 PDE4D (0.49) PDE4DESR2ESR1MAPTKMT2A
SCHEMBL17456246 0.88 ESR1 (0.49) PDE4DESR2ESR1MAPTKMT2A
SCHEMBL20414407 0.88 KMT2A (0.53) PDE4DESR2ESR1MAPTKMT2A
SCHEMBL18184910 0.87 PDK2 (0.55) PDE4DESR2ESR1ABL1ABCB1
SCHEMBL9229705 0.86 ESR1 (0.50) PDE4DESR2ESR1MAPTKMT2A
SCHEMBL3629040 0.86 LTA4H (0.53) PDE4DESR2ESR1MAPTKMT2A
SCHEMBL22651766 0.86 LTA4H (0.53) PDE4DESR2ESR1MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114276530-A Intermittent phosgene interface method preparation process of polycarbonate and application thereof 深圳市德力塑化工科技有限公司 2022-04-05 CN claimed
US-20260001987-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF MITSUBISHI CHEMICAL CORPORATION (JP) 2026-01-01 US disclosed
US-12460048-B2 Thermoplastic resin composition and formed product MITSUBISHI CHEMICAL CORPORATION (JP) 2025-11-04 US disclosed
EP-4023698-B1 THERMOPLASTIC RESIN COMPOSITION AND FORMED PRODUCT MITSUBISHI CHEM CORP (JP) 2025-10-22 EP disclosed
WO-2025079690-A1 POLYCARBONATE RESIN COMPOSITION, MOLDED BODY, PROJECTION BODY FOR XR, AND FILM FOR XR 三菱ケミカル株式会社 2025-04-17 WO disclosed
WO-2025079691-A1 COPOLYMERIZED POLYCARBONATE RESIN, POLYCARBONATE RESIN COMPOSITION, MOLDED ARTICLE, AND PROJECTION BODY FOR XR 三菱ケミカル株式会社 2025-04-17 WO disclosed
US-12180364-B2 Aromatic polycarbonate resin composition MITSUBISHI CHEMICAL CORPORATION (JP) 2024-12-31 US disclosed
EP-4477686-A1 POLYCARBONATE RESIN COMPOSITION Mitsubishi Chemical Corporation (JP) 2024-12-18 EP disclosed
US-20240376261-A1 POLYCARBONATE RESIN COMPOSITION MITSUBISHI CHEMICAL CORPORATION (JP) 2024-11-14 US disclosed
WO-2024204728-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF 三菱ケミカル株式会社 2024-10-03 WO disclosed
US-20080300378-A1 Method For Producing Polycarbonate Copolymer and Polycarbonate Copolymer IDEMITSU KOSAN CO., LTD. (JP) 2008-12-04 US disclosed
US-20080287610-A1 Copolycarbonate, Copolycarbonate Composition, and Optical molded Article Obtained Therefrom IDEMITSU KOSAN CO., LTD. (JP) 2008-11-20 US disclosed
US-20080221295-A1 Method for Producing Polycarbonate Copolymer IDEMITSU KOSAN CO., LTD. (JP) 2008-09-11 US disclosed
CN-100393803-C Polycarbonate resin composition and optical member IDEMITSU KOSAN CO (JP) 2008-06-11 CN disclosed
CN-1976974-A Method for producing polycarbonate copolymer and polycarbonate copolymer IDEMITSU KOSAN CO (JP) 2007-06-06 CN disclosed
EP-1764380-A1 METHOD FOR PRODUCING POLYCARBONATE COPOLYMER AND POLYCARBONATE COPOLYMER IDEMITSU KOSAN CO., LTD. (JP) 2007-03-21 EP disclosed
US-20070049724-A1 POLYETHERSULFONE COMPOSITIONS WITH HIGH HEAT AND GOOD IMPACT RESISTANCE GENERAL ELECTRIC COMPANY (US) 2007-03-01 US disclosed
CN-1918210-A Method for preparing polycarbonate copolymer IDEMITSU KOSAN CO (JP) 2007-02-21 CN disclosed
US-20070037906-A1 Polycarbonate resin composition and optical part IDEMITSU KOSAN CO., LTD. (JP) 2007-02-15 US disclosed
CN-1863871-A Polycarbonate resin composition and optical member IDEMITSU KOSAN CO (JP) 2006-11-15 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080221295-A1 Method for Producing Polycarbonate Copolymer HPD, CCNB1, CCNA1 PDE4D 4847/4885ESR2 1314/4885ESR1 293/4885
US-20260001987-A1 POLYCARBONATE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF SEM1, WDR1, TAF1 PDE4D 4739/4885ESR2 742/4885ESR1 890/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.