Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 18/20 | 0.71 |
| ▸ | HPGDS | O60760 | 1/20 | 0.55 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16649243 | 0.83 | DGAT1 (1.00) | DGAT1 | |
| SCHEMBL16787526 | 0.82 | DGAT1 (0.86) | DGAT1 | |
| SCHEMBL16660848 | 0.81 | DGAT1 (0.85) | DGAT1 | |
| SCHEMBL16660928 | 0.81 | DGAT1 (0.70) | DGAT1HPGDSSCN2A | |
| SCHEMBL16787568 | 0.76 | DGAT1 (0.86) | DGAT1 | |
| SCHEMBL16649120 | 0.76 | DGAT1 (0.86) | DGAT1 | |
| SCHEMBL16660896 | 0.75 | DGAT1 (0.85) | DGAT1 | |
| SCHEMBL16787550 | 0.75 | DGAT1 (0.85) | DGAT1 | |
| SCHEMBL16787572 | 0.75 | DGAT1 (0.85) | DGAT1 | |
| SCHEMBL20428480 | 0.75 | DGAT1 (0.65) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2862856-A1 | AROMATIC HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2015-04-22 | — | — | EP | disclosed |