Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 2/20 | 0.54 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.39 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2837726 | 0.95 | HPGDS (0.57) | HPGDSDHODHLDHAHSD17B1HSD17B2 | |
| SCHEMBL2837699 | 0.89 | CYP11B1 (0.51) | HPGDSLDHACYP11B1CYP11B2MAPK1 | |
| SCHEMBL2838619 | 0.88 | HPGDS (0.50) | HPGDSDHODHLDHACYP11B1CYP11B2 | |
| SCHEMBL2839049 | 0.88 | GSK3B (0.51) | HPGDSLDHACYP11B1CYP11B2 | |
| SCHEMBL16661139 | 0.86 | HPGDS (0.41) | HPGDSDHODHMAPK1DYRK1ADGAT1 | |
| SCHEMBL2314781 | 0.85 | HPGDS (0.50) | HPGDSDHODHHSD17B1HSD17B2CYP11B1 | |
| SCHEMBL7139559 | 0.85 | HPGDS (0.43) | HPGDS | |
| SCHEMBL4847155 | 0.85 | HPGDS (0.43) | HPGDS | |
| SCHEMBL528246 | 0.85 | MEN1 (0.46) | HPGDSMAPK1 | |
| SCHEMBL2834537 | 0.84 | HPGDS (0.52) | HPGDSDHODHLDHA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2862856-A1 | AROMATIC HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2015-04-22 | — | — | EP | disclosed |