Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 19/20 | 0.49 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16787853 | 0.89 | DGAT1 (0.62) | DGAT1SOAT1FAAHCHRM2DGAT2 | |
| SCHEMBL16660895 | 0.81 | DGAT1 (0.71) | DGAT1 | |
| SCHEMBL16661340 | 0.77 | DGAT1 (0.59) | DGAT1SOAT1FAAHCHRM2DGAT2 | |
| SCHEMBL16787840 | 0.73 | DGAT1 (0.58) | DGAT1SOAT1 | |
| SCHEMBL16661339 | 0.72 | DGAT1 (0.60) | DGAT1SOAT1FAAHCHRM2DGAT2 | |
| SCHEMBL16661335 | 0.71 | DGAT1 (0.43) | DGAT1SOAT1 | |
| SCHEMBL16660856 | 0.69 | DGAT1 (0.68) | DGAT1 | |
| SCHEMBL180618 | 0.67 | DGAT1 (0.67) | DGAT1SOAT1FAAHCHRM2DGAT2 | |
| SCHEMBL902157 | 0.67 | DGAT1 (0.75) | DGAT1SOAT1 | |
| SCHEMBL16787659 | 0.67 | DGAT1 (0.85) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2862856-A1 | AROMATIC HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2015-04-22 | — | — | EP | disclosed |