Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 8/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16790070 | 0.83 | DGAT1 (0.46) | DGAT1KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL16790071 | 0.82 | DGAT1 (0.47) | DGAT1KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL16660871 | 0.81 | DGAT1 (0.45) | DGAT1KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL16660864 | 0.79 | DGAT1 (0.45) | DGAT1KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL16790126 | 0.78 | DGAT1 (0.46) | DGAT1KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL16790125 | 0.76 | DGAT1 (0.47) | DGAT1KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL16787668 | 0.72 | DGAT1 (0.50) | DGAT1KDM4EHPGDL3MBTL1MAPT | |
| SCHEMBL20428490 | 0.71 | DGAT1 (0.56) | DGAT1KDM4EALDH1A1HPGDL3MBTL1 | |
| SCHEMBL16787672 | 0.71 | DGAT1 (0.51) | DGAT1MAPT | |
| SCHEMBL16787732 | 0.69 | DGAT1 (0.47) | DGAT1KDM4EALDH1A1HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2862856-A1 | AROMATIC HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2015-04-22 | — | — | EP | disclosed |