Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 8/20 | 0.80 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.37 |
| ▸ | FEN1 | P39748 | 5/20 | 0.37 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16661013 | 0.89 | DGAT1 (1.00) | DGAT1ALOX5APFEN1 | |
| SCHEMBL16661005 | 0.87 | DGAT1 (0.72) | DGAT1ALOX5APFEN1F2RL1NPC1 | |
| SCHEMBL16661026 | 0.85 | DGAT1 (1.00) | DGAT1ALOX5APFEN1NPC1 | |
| SCHEMBL16661015 | 0.83 | DGAT1 (0.56) | DGAT1F2RL1 | |
| SCHEMBL16661003 | 0.82 | DGAT1 (0.75) | DGAT1ALOX5APFEN1 | |
| SCHEMBL16661007 | 0.82 | DGAT1 (0.66) | DGAT1ALOX5APFEN1 | |
| SCHEMBL16661009 | 0.80 | DGAT1 (0.64) | DGAT1ALOX5APFEN1F2RL1 | |
| SCHEMBL10276697 | 0.77 | DGAT1 (0.59) | DGAT1ALOX5APFEN1NPC1 | |
| SCHEMBL21064882 | 0.76 | DGAT1 (0.78) | DGAT1ALOX5APFEN1 | |
| SCHEMBL1441479 | 0.75 | DGAT1 (0.57) | DGAT1ALOX5APFEN1F2RL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2862856-A1 | AROMATIC HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2015-04-22 | — | — | EP | disclosed |