Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 3/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.39 |
| ▸ | AHR | P35869 | 6/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16660927 | 0.84 | DGAT1 (0.53) | NR1H2NR1H3DGAT1AHRTP53 | |
| SCHEMBL21064877 | 0.84 | DGAT1 (0.56) | NR1H2NR1H3DGAT1AHRTP53 | |
| SCHEMBL21939062 | 0.81 | DGAT1 (0.30) | DGAT1 | |
| SCHEMBL18552901 | 0.80 | NR1H2 (0.40) | NR1H2NR1H3DGAT1AHRPTGS2 | |
| SCHEMBL16661188 | 0.79 | NR1H2 (0.41) | NR1H2NR1H3DGAT1AHRTP53 | |
| SCHEMBL25791975 | 0.78 | NR1H3 (0.57) | NR1H2NR1H3AHRTP53MAPT | |
| SCHEMBL16661370 | 0.78 | DGAT1 (0.39) | DGAT1L3MBTL1 | |
| SCHEMBL16661332 | 0.75 | NR1H2 (0.34) | NR1H2NR1H3AHRL3MBTL1 | |
| SCHEMBL21064876 | 0.72 | DGAT1 (0.51) | DGAT1 | |
| SCHEMBL20169321 | 0.71 | DGAT1 (0.56) | DGAT1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2862856-A1 | AROMATIC HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2015-04-22 | — | — | EP | disclosed |