Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 16/20 | 0.58 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.49 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | NNMT | P40261 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16660947 | 0.89 | MKNK1 (0.63) | DGAT1MKNK1MKNK2AAK1SOAT1 | |
| SCHEMBL16661050 | 0.87 | DGAT1 (0.59) | DGAT1MKNK1MKNK2AAK1 | |
| SCHEMBL18541134 | 0.85 | DGAT1 (0.62) | DGAT1MKNK1MKNK2AAK1SOAT1 | |
| SCHEMBL16661033 | 0.85 | DGAT1 (0.62) | DGAT1MKNK1MKNK2SOAT1KCNH2 | |
| SCHEMBL10007447 | 0.84 | DGAT1 (0.60) | DGAT1MKNK1MKNK2AAK1SOAT1 | |
| SCHEMBL16661020 | 0.82 | DGAT1 (0.59) | DGAT1MKNK1MKNK2SOAT1KCNH2 | |
| SCHEMBL20428788 | 0.82 | DGAT1 (0.54) | DGAT1MKNK1MKNK2AAK1 | |
| SCHEMBL16661278 | 0.81 | DGAT1 (0.58) | DGAT1MKNK1MKNK2AAK1SOAT1 | |
| SCHEMBL20428515 | 0.81 | DGAT1 (0.58) | DGAT1MKNK1MKNK2AAK1SOAT1 | |
| SCHEMBL10176555 | 0.81 | DGAT1 (0.52) | DGAT1MKNK1MKNK2SOAT1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2862856-A1 | AROMATIC HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2015-04-22 | — | — | EP | disclosed |