Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18432300 | 0.90 | GAA (0.46) | GAAABL1HTTPTGS2MAPT | |
| SCHEMBL19045818 | 0.90 | GAA (0.50) | GAAABL1HTTPTGS2MAPT | |
| SCHEMBL7863946 | 0.90 | GAA (0.50) | GAAABL1HTTPTGS2MAPT | |
| SCHEMBL1953848 | 0.87 | GAA (0.58) | GAAABL1HTTMAPTLMNA | |
| SCHEMBL168271 | 0.86 | CA12 (0.50) | GAAABL1HTTPTGS2LMNA | |
| SCHEMBL7177999 | 0.86 | CA12 (0.50) | GAAABL1HTTPTGS2MAPT | |
| SCHEMBL13696490 | 0.85 | GAA (0.63) | GAAHTTMAPTLMNASMN1; SMN2 | |
| SCHEMBL3689533 | 0.85 | GAA (0.46) | GAAABL1HTTPTGS2MAPT | |
| SCHEMBL4857922 | 0.85 | GAA (0.42) | GAAABL1HTTPTGS2MAPT | |
| SCHEMBL17030839 | 0.85 | ABL1 (0.57) | GAAABL1MAPTHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2526096-B1 | 4-PHENOXY-NICOTINAMIDE OR 4-PHENOXY-PYRIMIDINE-5-CARBOXAMIDE COMPOUNDS | HOFFMANN LA ROCHE (CH) | 2015-04-22 | — | — | EP | disclosed |
| US-20140012017-A1 | ORGANIC SEMICONDUCTOR COMPOUND, SEMICONDUCTOR DEVICE, SOLAR CELL AND PRODUCING METHOD OF ORGANIC SEMICONDUCTOR COMPOUND | NAT INST FOR MATERIALS SCIENCE (JP) | 2014-01-09 | — | — | US | disclosed |