SCHEMBL166639

SCHEMBL166639

COc1cc(C(Cl)(Cl)Cl)cc(Cl)n1

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PDE2A O00408 1/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
TAS1R3 Q7RTX0 1/20 0.35
TAS1R1 Q7RTX1 1/20 0.35
TAS1R2 Q8TE23 1/20 0.35
LMNA P02545 2/20 0.34
HSP90AA1 P07900 2/20 0.34
HSP90AB1 P08238 2/20 0.34
ALDH1A1 P00352 3/20 0.34
KDM4E B2RXH2 1/20 0.33
L3MBTL1 Q9Y468 2/20 0.32
EDNRB P24530 1/20 0.32
EDNRA P25101 1/20 0.32
HTT P42858 1/20 0.32
CYP1A2 P05177 2/20 0.32
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11325427 0.87 ALDH1A1 (0.42) PDE2ASMN1; SMN2LMNAALDH1A1KDM4E
SCHEMBL11727143 0.85 SMN1; SMN2 (0.33) PDE2ASMN1; SMN2TAS1R3TAS1R1TAS1R2
SCHEMBL13990720 0.84 SMN1; SMN2 (0.35) PDE2ASMN1; SMN2TAS1R3TAS1R1TAS1R2
SCHEMBL1437397 0.82 TACR1 (0.38) SMN1; SMN2TAS1R3TAS1R1TAS1R2ALDH1A1
SCHEMBL11068771 0.81 SMN1; SMN2 (0.36) SMN1; SMN2TAS1R3TAS1R1TAS1R2LMNA
SCHEMBL11728011 0.80 AR (0.35) PDE2ASMN1; SMN2LMNAALDH1A1KDM4E
SCHEMBL11179412 0.79 NPC1 (0.34) SMN1; SMN2ALDH1A1EDNRBEDNRAKMT2A
SCHEMBL11335300 0.79 S1PR2 (0.34) ALDH1A1L3MBTL1
SCHEMBL11726771 0.78 PDE2A (0.34) PDE2ASMN1; SMN2LMNAALDH1A1KDM4E
SCHEMBL11066943 0.78 SMN1; SMN2 (0.33) SMN1; SMN2TAS1R3TAS1R1TAS1R2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3209 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3060043-B1 PESTICIDAL COMPOSITIONS AND RELATED METHODS CORTEVA AGRISCIENCE LLC (US) 2025-11-26 EP claimed
EP-3578542-B1 COMPOSITIONS HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-12 EP claimed
EP-3578543-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-08-20 EP claimed
EP-3578541-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY, AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-05-28 EP claimed
US-20240188569-A1 NEW YEAST STRAIN AND ITS USES FOR THE CONTROL OF PHYTOPATHOGENS AGROVENTURES LLC (US) 2024-06-13 US claimed
US-20240138408-A1 COMPOSITION COMPRISING BENZYLAMINE ACARICIDE AND USE THEREOF SHANGDONG KANGIAO BIO-TECHNOLOGY CO., LTD (CN) 2024-05-02 US claimed
EP-4323496-A1 NEW YEAST STRAIN AND ITS USES FOR THE CONTROL OF PHYTOPATHOGENS AGROVENTURES S.R.L. (IT) 2024-02-21 EP claimed
WO-2023212494-A2 PREDICTIVE PESTICIDE RESISTANCE INFORMATION GENERATION AND USE PIONEER HI-BRED INTERNATIONAL, INC. (US) 2023-11-02 WO claimed
EP-4255175-A1 PREDICTIVE PESTICIDE RESISTANCE MAP GENERATION AND USE Pioneer Hi-Bred International, Inc. (US) 2023-10-11 EP claimed
WO-2022219505-A1 NEW YEAST STRAIN AND ITS USES FOR THE CONTROL OF PHYTOPATHOGENS AGROVENTURES S.R.L. (IT) 2022-10-20 WO claimed
WO-2010030824-A1 GELATINOUS ELASTOMER COMPOSITIONS SILIPOS, INC. (US) 2010-03-18 WO claimed
US-20100063008-A1 GELATINOUS ELASTOMER COMPOSITIONS SILIPOS, INC. (US) 2010-03-11 US claimed
EP-1045065-B1 Cellulose fiber-containing structure TORAY INDUSTRIES (JP) 2006-05-17 EP claimed
US-6540792-B1 Shape stability and antimicrobial property excellent in industrial washing durability; cellulose fibers crosslinked and having given crosslinking index and synthetic fibers containing an antimicrobial agent TORAY INDUSTRIES, INC. (JP) 2003-04-01 US claimed
US-20020018794-A1 Clothing TORAY INDUSTRIES, INC., A CORPORATION OF JAPAN (JP) 2002-02-14 US claimed
WO-2001056358-A2 ENHANCED PROPERTIED PESTICIDES ROHM AND HAAS COMPANY (US) 2001-08-09 WO claimed
EP-1045065-A1 Cellulose fiber-containing structure TORAY INDUSTRIES, INC. (JP) 2000-10-18 EP claimed
CN-1239162-A Molded antimicrobial article, and production process thereof TORAY INDUSTRIES (JP) 1999-12-22 CN claimed
EP-0952248-A2 A molded antimicrobial article and a process for its production TORAY INDUSTRIES, INC. (JP) 1999-10-27 EP claimed
US-4062962-A Substituted pyridines as systemic plant protectants THE DOW CHEMICAL COMPANY (US) 1977-12-13 US claimed