Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 7/20 | 0.41 |
| ▸ | RAB9A | P51151 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9913314 | 0.84 | EPHX1 (0.41) | EPHX1NPC1RAB9AALDH1A1ALOX12 | |
| SCHEMBL13391356 | 0.84 | EPHX1 (0.41) | EPHX1NPC1RAB9AALDH1A1ALOX12 | |
| SCHEMBL12557558 | 0.84 | EPHX1 (0.41) | EPHX1NPC1RAB9AALDH1A1ALOX12 | |
| SCHEMBL2111012 | 0.83 | EPHX1 (0.44) | EPHX1NPC1RAB9AALDH1A1ALOX12 | |
| SCHEMBL9913317 | 0.78 | EPHX1 (0.41) | EPHX1NPC1RAB9AALDH1A1ALOX12 | |
| SCHEMBL9913310 | 0.78 | EPHX1 (0.43) | EPHX1NPC1RAB9AALDH1A1ALOX12 | |
| SCHEMBL2108797 | 0.78 | EPHX1 (0.41) | EPHX1NPC1RAB9AALDH1A1ALOX12 | |
| SCHEMBL8034193 | 0.78 | EPHX1 (0.41) | EPHX1NPC1RAB9AALDH1A1ALOX12 | |
| SCHEMBL2108798 | 0.78 | EPHX1 (0.41) | EPHX1NPC1RAB9AALDH1A1ALOX12 | |
| SCHEMBL7924322 | 0.78 | EPHX1 (0.43) | EPHX1NPC1RAB9AALDH1A1ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2332943-B1 | NOVEL FUSED AMINODIHYDROTHIAZINE DERIVATIVE | EISAI R&D MAN CO LTD (JP) | 2015-04-22 | — | — | EP | disclosed |