Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2108798 | 1.00 | EPHX1 (0.41) | EPHX1ALDH1A1SMN1; SMN2GAALMNA | |
| SCHEMBL2108797 | 1.00 | EPHX1 (0.41) | EPHX1ALDH1A1SMN1; SMN2GAALMNA | |
| SCHEMBL11293044 | 0.91 | EPHX1 (0.42) | EPHX1ALDH1A1SMN1; SMN2LMNAMAPT | |
| SCHEMBL2619901 | 0.90 | EPHX1 (0.39) | EPHX1ALDH1A1SMN1; SMN2GAALMNA | |
| SCHEMBL2108331 | 0.90 | EPHX1 (0.39) | EPHX1ALDH1A1SMN1; SMN2GAALMNA | |
| SCHEMBL3773875 | 0.90 | EPHX1 (0.39) | EPHX1ALDH1A1SMN1; SMN2GAALMNA | |
| SCHEMBL2631696 | 0.90 | EPHX1 (0.39) | EPHX1ALDH1A1SMN1; SMN2GAALMNA | |
| SCHEMBL3803423 | 0.89 | EPHX1 (0.42) | EPHX1ALDH1A1SMN1; SMN2GAALMNA | |
| SCHEMBL2631629 | 0.89 | EPHX1 (0.42) | EPHX1ALDH1A1SMN1; SMN2GAALMNA | |
| SCHEMBL18597910 | 0.89 | EPHX1 (0.42) | EPHX1ALDH1A1SMN1; SMN2GAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009091016-A1 | CONDENSED AMINODIHYDROTHIAZINE DERIVATIVE | EISAI R & D MANAGEMENT CO., LTD. (JP) | 2009-07-23 | — | — | WO | disclosed |