Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13241014 | 1.00 | GAA (0.50) | GAAALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2484664 | 1.00 | GAA (0.50) | GAAALDH1A1RAB9ANPC1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2486567 | 0.98 | GAA (0.49) | GAAALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL2488739 | 0.92 | SMN1; SMN2 (0.47) | GAAALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL3216199 | 0.89 | MEN1 (0.48) | GAAALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9290194 | 0.89 | SMN1; SMN2 (0.46) | GAAALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL839473 | 0.89 | MEN1 (0.50) | GAAALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7578154 | 0.88 | GAA (0.43) | GAAALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7578049 | 0.87 | GAA (0.42) | GAAALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL840113 | 0.86 | MAOB (0.48) | GAAALDH1A1RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376489-B1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | CHIESI FARMA SPA (IT) | 2015-04-22 | — | — | EP | disclosed |