Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RPS6KB1 | P23443 | 2/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13241014 | 0.87 | GAA (0.50) | GAAALDH1A1SMN1; SMN2LMNARAB9A | |
| SCHEMBL2484664 | 0.87 | GAA (0.50) | GAAALDH1A1SMN1; SMN2LMNARAB9A | |
| SCHEMBL16664407 | 0.87 | GAA (0.50) | GAAALDH1A1SMN1; SMN2LMNARAB9A | |
| SCHEMBL7578154 | 0.86 | GAA (0.43) | GAAALDH1A1SMN1; SMN2LMNARAB9A | |
| Hydrochloric Acid SCHEMBL2486567 | 0.85 | GAA (0.49) | GAAALDH1A1SMN1; SMN2LMNARAB9A | |
| SCHEMBL7576115 | 0.80 | KMT2A (0.46) | GAAALDH1A1LMNARPS6KB1AURKA | |
| SCHEMBL7584286 | 0.80 | ALDH1A1 (0.48) | GAAALDH1A1SMN1; SMN2LMNARAB9A | |
| SCHEMBL2488739 | 0.79 | SMN1; SMN2 (0.47) | GAAALDH1A1SMN1; SMN2LMNARAB9A | |
| SCHEMBL7575977 | 0.78 | GAA (0.54) | GAAALDH1A1LMNARAB9ANPC1 | |
| SCHEMBL3216199 | 0.77 | MEN1 (0.48) | GAAALDH1A1SMN1; SMN2LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242069-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001003684-A2 | ALBUMIN-BINDING COMPOUNDS THAT PREVENT NONENZYMATIC GLYCATION AND THAT MAY BE USED FOR TREATMENT OF GLYCATION-RELATED PATHOLOGIES | EXOCELL, INC. (US) | 2001-01-18 | — | — | WO | disclosed |