Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NQO2 | P16083 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | F7 | P08709 | 1/20 | 0.47 |
| ▸ | F3 | P13726 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2482992 | 1.00 | HSD17B10 (0.53) | HSD17B10NAPRTPOLBMAPTALDH1A1 | |
| SCHEMBL13240806 | 1.00 | HSD17B10 (0.53) | HSD17B10NAPRTPOLBMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL2483476 | 0.98 | HSD17B10 (0.51) | HSD17B10NAPRTPOLBMAPTALDH1A1 | |
| SCHEMBL2993388 | 0.85 | POLB (0.65) | POLBMAPTALDH1A1RAB9ACYP1A2 | |
| SCHEMBL13240808 | 0.84 | MAPT (0.52) | HSD17B10NAPRTPOLBMAPTALDH1A1 | |
| SCHEMBL2484912 | 0.84 | MAPT (0.52) | HSD17B10NAPRTPOLBMAPTALDH1A1 | |
| SCHEMBL27736457 | 0.83 | HSD17B10 (0.55) | HSD17B10NAPRTPOLBMAPTALDH1A1 | |
| SCHEMBL7574752 | 0.81 | NPSR1 (0.53) | HSD17B10POLBMAPTALDH1A1CYP1A2 | |
| SCHEMBL2483519 | 0.80 | FPR2 (0.49) | HSD17B10POLBMAPTALDH1A1KDM4E | |
| SCHEMBL146704 | 0.80 | FPR2 (0.49) | HSD17B10POLBMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2376489-B1 | ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF | CHIESI FARMA SPA (IT) | 2015-04-22 | — | — | EP | disclosed |