Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13631330 | 0.91 | BTK (0.37) | BTKMAOBMAOAKDM1ASYK | |
| SCHEMBL13618997 | 0.91 | BTK (0.37) | BTKMAOBMAOAKDM1ASYK | |
| SCHEMBL13618973 | 0.91 | BTK (0.37) | BTKMAOBMAOAKDM1ASYK | |
| SCHEMBL13618991 | 0.88 | MAOB (0.39) | BTKMAOBMAOAKDM1ASYK | |
| SCHEMBL16668084 | 0.85 | BTK (0.51) | BTKMAOBMAOAKDM1ASYK | |
| SCHEMBL19783843 | 0.85 | BTK (0.51) | BTKMAOBMAOAKDM1ASYK | |
| SCHEMBL13618972 | 0.85 | BTK (0.51) | BTKMAOBMAOAKDM1ASYK | |
| SCHEMBL13748220 | 0.85 | BTK (0.51) | BTKMAOBMAOAKDM1ASYK | |
| SCHEMBL13696102 | 0.82 | BTK (0.37) | BTKMAOBMAOAKDM1ASYK | |
| SCHEMBL30951784 | 0.82 | BTK (0.37) | BTKMAOBMAOAKDM1ASYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2407450-B1 | Method for producing optically active diamine derivative | DAIICHI SANKYO CO LTD (JP) | 2015-04-22 | — | — | EP | disclosed |