Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 5/20 | 0.39 |
| ▸ | AKT1 | P31749 | 3/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 6/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16666394 | 1.00 | PTPN1 (0.39) | PTPN1AKT1PSEN1MEN1KMT2A | |
| SCHEMBL16666419 | 0.81 | AKT1 (0.52) | PTPN1AKT1PSEN1MEN1KMT2A | |
| SCHEMBL16666423 | 0.81 | AKT1 (0.52) | PTPN1AKT1PSEN1MEN1KMT2A | |
| SCHEMBL16666422 | 0.81 | AKT1 (0.52) | PTPN1AKT1PSEN1MEN1KMT2A | |
| SCHEMBL14544421 | 0.76 | PSEN1 (0.50) | PTPN1AKT1PSEN1MEN1KMT2A | |
| SCHEMBL16666352 | 0.74 | PSEN1 (0.40) | PTPN1PSEN1 | |
| SCHEMBL16667485 | 0.73 | DNTT (0.41) | PSEN1KMT2A | |
| SCHEMBL16667486 | 0.73 | DNTT (0.41) | PSEN1KMT2A | |
| SCHEMBL16666546 | 0.70 | PTGS1 (0.39) | PSEN1 | |
| SCHEMBL5838691 | 0.70 | MEN1 (0.45) | PTPN1AKT1PSEN1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2865677-B1 | Synthesis of chromane compounds and their derivatives by a copper-catalyzed conjugate addition reaction | DSM IP ASSETS BV (NL) | 2016-11-23 | — | — | EP | disclosed |
| WO-2015059129-A1 | SYNTHESIS OF CHROMANE COMPOUNDS AND THEIR DERIVATIVES BY A COPPER-CATALYZED CONJUGATE ADDITION REACTION | DSM IP ASSETS B.V. (NL) | 2015-04-30 | — | — | WO | disclosed |
| EP-2865677-A1 | Synthesis of chromane compounds and their derivatives by a copper-catalyzed conjugate addition reaction | DSM IP Assets B.V. (NL) | 2015-04-29 | — | — | EP | disclosed |