SCHEMBL16667196

SCHEMBL16667196

CCS(=O)(=O)c1ccc(-c2nc3cc(C(F)(F)C(F)(F)F)cnc3n2C)cc1

nearest known ligand 0.40

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ POLB P06746 1/20 0.40
▸ ACSS2 Q9NR19 1/20 0.39
▸ CA1 P00915 2/20 0.39
▸ CA2 P00918 2/20 0.39
▸ CA12 O43570 1/20 0.39
▸ CA9 Q16790 1/20 0.39
▸ KCNH2 Q12809 1/20 0.38
▸ SYK P43405 1/20 0.37
▸ RORC P51449 6/20 0.37
▸ GABRA2 P47869 2/20 0.36
▸ NR1H2 P55055 1/20 0.36
▸ PTGS2 P35354 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29431634 0.82 POLB (0.40) POLBACSS2NR1H2
SCHEMBL15862663 0.82 POLB (0.40) POLBACSS2NR1H2
SCHEMBL10281048 0.82 POLB (0.38) POLBACSS2NR1H2
SCHEMBL29431646 0.80 POLB (0.37) POLBACSS2NR1H2PTGS2
SCHEMBL14684600 0.80 POLB (0.37) POLBACSS2NR1H2PTGS2
SCHEMBL30205922 0.80 POLB (0.37) POLBACSS2
SCHEMBL27172666 0.80 POLB (0.37) POLBACSS2
SCHEMBL14684615 0.80 POLB (0.45) POLBRORCNR1H2
SCHEMBL29431643 0.80 POLB (0.45) POLBRORCNR1H2
SCHEMBL15868339 0.80 POLB (0.38) POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150148308-A1 PEST CONTROL COMPOSITION FOR HARMFUL ARTHROPODS, AND PEST CONTROL METHOD FOR HARMFUL ARTHROPODS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-05-28 — — US disclosed
EP-2865266-A1 PEST CONTROL COMPOSITION FOR HARMFUL ARTHROPODS, AND PEST CONTROL METHOD FOR HARMFUL ARTHROPODS Sumitomo Chemical Company, Limited (JP) 2015-04-29 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150148308-A1 PEST CONTROL COMPOSITION FOR HARMFUL ARTHROPODS, AND PEST CONTROL METHOD FOR HARMFUL ARTHROPODS SFXN1, OSR1, PIR POLB 4471/4885ACSS2 3664/4885CA1 3113/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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