SCHEMBL16667274

SCHEMBL16667274

O=C(O)NCCCCCCCCCCCCNc1c2c(nc3cc(Cl)ccc13)CCCC2

nearest known ligand 0.81

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ACHE P22303 4/20 0.81
BCHE P06276 3/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16667433 1.00 ACHE (0.81) ACHEBCHE
SCHEMBL14125685 1.00 ACHE (0.81) ACHEBCHE
SCHEMBL14125906 0.93 ACHE (0.69) ACHEBCHE
SCHEMBL16667400 0.93 ACHE (0.69) ACHEBCHE
SCHEMBL16667372 0.93 ACHE (0.69) ACHEBCHE
SCHEMBL14127868 0.93 BCHE (0.71) ACHEBCHE
SCHEMBL22470350 0.88 ACHE (0.79) ACHEBCHE
SCHEMBL3373894 0.88 BCHE (0.81) ACHEBCHE
SCHEMBL3373226 0.88 BCHE (0.81) ACHEBCHE
SCHEMBL3371927 0.88 BCHE (0.81) ACHEBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2714658-B1 NOVEL HYBRID CHOLINESTERASE INHIBITORS UNIV WARSZAWSKI (PL) 2015-04-29 EP claimed
EP-2714658-B1 NOVEL HYBRID CHOLINESTERASE INHIBITORS UNIV WARSZAWSKI (PL) 2015-04-29 EP disclosed