SCHEMBL16667484

SCHEMBL16667484

C=CCC1OCCC(C)(C)O1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10741207 0.74
SCHEMBL504033 0.71
SCHEMBL19523377 0.71 TDP1 (0.36)
SCHEMBL15649742 0.71
SCHEMBL11285073 0.70
SCHEMBL6277553 0.68
SCHEMBL2103164 0.68
SCHEMBL8651577 0.67
SCHEMBL2050270 0.63
SCHEMBL24638635 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3131888-B1 PRODUCTION OF STARTING MATERIALS CONTAINING 2-SUBSTITUTED 4-HYDROXY-4-METHYL-TETRAHYDROPYRANES FROM 2-ALKYL-4,4-DIMETHYL-1,3-DIOXANE BASF SE (DE) 2022-08-03 EP disclosed
EP-3131888-B1 PRODUCTION OF STARTING MATERIALS CONTAINING 2-SUBSTITUTED 4-HYDROXY-4-METHYL-TETRAHYDROPYRANES FROM 2-ALKYL-4,4-DIMETHYL-1,3-DIOXANE BASF SE (DE) 2022-08-03 EP disclosed
CN-106170483-B 4- hydroxy-4-methyl-oxinane is replaced by the raw material preparation 2- comprising 2- alkyl -4,4- dimethyl -1,3- dioxanes 巴斯夫欧洲公司 2019-08-02 CN disclosed
CN-106164062-B 4- methyl-tetrahydro pyrans is replaced by the raw material preparation 2- comprising 2- alkyl -4,4- dimethyl -1,3- dioxanes 巴斯夫欧洲公司 2019-04-19 CN disclosed
US-10233169-B2 Production of 2-substituted 4-hydroxy-4-methyl-tetrahydropyrans from starting materials containing 2-alkyl-4,4-dimethyl-1,3-dioxanes BASF SE (DE) 2019-03-19 US disclosed
US-10233169-B2 Production of 2-substituted 4-hydroxy-4-methyl-tetrahydropyrans from starting materials containing 2-alkyl-4,4-dimethyl-1,3-dioxanes BASF SE (DE) 2019-03-19 US disclosed
US-10233169-B2 Production of 2-substituted 4-hydroxy-4-methyl-tetrahydropyrans from starting materials containing 2-alkyl-4,4-dimethyl-1,3-dioxanes BASF SE (DE) 2019-03-19 US disclosed
EP-3131885-B1 PREPARATION OF 2-SUBSTITUTED 4-METHYL-TETRAHYDROPYRANES FROM STARTING MATERIALS CONTAINING 2-ALKYL-4,4-DIMETHYL-1,3-DIOXANE BASF SE (DE) 2019-01-09 EP disclosed
EP-3131885-B1 PREPARATION OF 2-SUBSTITUTED 4-METHYL-TETRAHYDROPYRANES FROM STARTING MATERIALS CONTAINING 2-ALKYL-4,4-DIMETHYL-1,3-DIOXANE BASF SE (DE) 2019-01-09 EP disclosed
US-9994540-B2 Production of 2-substituted 4-methyl-tetrahydropyrans from starting materials containing 2-alkyl-4,4-dimethyl-1,3-dioxanes BASF SE (DE) 2018-06-12 US disclosed
US-20170037022-A1 PRODUCTION OF 2-SUBSTITUTED 4-HYDROXY-4-METHYL-TETRAHYDROPYRANS FROM STARTING MATERIALS CONTAINING 2-ALKYL-4,4-DIMETHYL-1,3-DIOXANES BASF SE (DE) 2017-02-09 US disclosed
CN-106170483-A 2 replacement 4 hydroxyl 4 methyl Pentamethylene oxide .s are prepared by the raw material comprising 2 alkyl 4,4 dimethyl 1,3 dioxanes 巴斯夫欧洲公司 2016-11-30 CN disclosed
CN-106164062-A The raw material comprising 2 alkyl 4,4 dimethyl 1,3 dioxanes is prepared 2 replacement 4 methyl oxinanes 巴斯夫欧洲公司 2016-11-23 CN disclosed
WO-2015158584-A1 PRODUCTION OF 2-SUBSTITUTED 4-METHYL-TETRAHYDROPYRANS FROM STARTING MATERIALS CONTAINING 2-ALKYL-4,4-DIMETHYL-1,3-DIOXANES BASF SE (DE) 2015-10-22 WO disclosed
WO-2015158584-A1 PRODUCTION OF 2-SUBSTITUTED 4-METHYL-TETRAHYDROPYRANS FROM STARTING MATERIALS CONTAINING 2-ALKYL-4,4-DIMETHYL-1,3-DIOXANES BASF SE (DE) 2015-10-22 WO disclosed
WO-2015158585-A1 PRODUCTION OF 2-SUBSTITUTED 4-HYDROXY-4-METHYL-TETRAHYDROPYRANS FROM STARTING MATERIALS CONTAINING 2-ALKYL-4,4-DIMETHYL-1,3-DIOXANES BASF SE (DE) 2015-10-22 WO disclosed
WO-2015158585-A1 PRODUCTION OF 2-SUBSTITUTED 4-HYDROXY-4-METHYL-TETRAHYDROPYRANS FROM STARTING MATERIALS CONTAINING 2-ALKYL-4,4-DIMETHYL-1,3-DIOXANES BASF SE (DE) 2015-10-22 WO disclosed
WO-2015158585-A1 PRODUCTION OF 2-SUBSTITUTED 4-HYDROXY-4-METHYL-TETRAHYDROPYRANS FROM STARTING MATERIALS CONTAINING 2-ALKYL-4,4-DIMETHYL-1,3-DIOXANES BASF SE (DE) 2015-10-22 WO disclosed
EP-2865676-A1 Preparation of 2-substituted 4-methyl-tetrahydropyranes from starting materials containing 2-alkyl-4,4-dimethyl-1,3-dioxane BASF SE (DE) 2015-04-29 EP disclosed
EP-2865676-A1 Preparation of 2-substituted 4-methyl-tetrahydropyranes from starting materials containing 2-alkyl-4,4-dimethyl-1,3-dioxane BASF SE (DE) 2015-04-29 EP disclosed