SCHEMBL16667828

SCHEMBL16667828

COC(=O)C(C)NC(=O)C(C)NC(=O)OC(C)(C)C

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.53
CA14 Q9ULX7 1/20 0.53
KMT2A Q03164 1/20 0.46
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA7 P43166 1/20 0.45
PSENEN Q9NZ42 1/20 0.43
CTSK P43235 5/20 0.42
CTSS P25774 4/20 0.42
GLA P06280 2/20 0.41
KDM4E B2RXH2 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41
HPGD P15428 1/20 0.41
GLS O94925 1/20 0.41
CYP2D6 P10635 1/20 0.41
CTSL P07711 1/20 0.40
CTSB P07858 1/20 0.40
EPHX2 P34913 1/20 0.40
BIRC2 Q13490 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26030105 1.00 CA12 (0.53) CA12CA14KMT2ACA1CA2
SCHEMBL13112912 1.00 CA12 (0.53) CA12CA14KMT2ACA1CA2
SCHEMBL21737876 1.00 CA12 (0.53) CA12CA14KMT2ACA1CA2
SCHEMBL30134977 1.00 CA12 (0.53) CA12CA14KMT2ACA1CA2
SCHEMBL9137141 1.00 CA12 (0.53) CA12CA14KMT2ACA1CA2
SCHEMBL709981 0.93 CA14 (0.59) CA12CA14KMT2ACA1CA2
SCHEMBL241988 0.93 CA14 (0.59) CA12CA14KMT2ACA1CA2
SCHEMBL2380555 0.93 CA14 (0.59) CA12CA14KMT2ACA1CA2
SCHEMBL29918031 0.91 KMT2A (0.47) CA12CA14KMT2ACA1CA2
SCHEMBL29918107 0.91 KMT2A (0.47) CA12CA14KMT2ACA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150119251-A1 AGRICULTURAL PLANT-PROTECTING AGENTS CONTAINING DIPEPTIDE DERIVATIVE AS ACTIVE INGREDIENT REPUBLIC OF KOREA (RURAL DEVELOPMENT ADMINISTRATION) (KR) 2015-04-30 US claimed
CN-116096413-A Anti-human VISTA antibodies and uses thereof 伊穆奈克斯特股份有限公司 2023-05-09 CN disclosed
US-20150119251-A1 AGRICULTURAL PLANT-PROTECTING AGENTS CONTAINING DIPEPTIDE DERIVATIVE AS ACTIVE INGREDIENT REPUBLIC OF KOREA (RURAL DEVELOPMENT ADMINISTRATION) (KR) 2015-04-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150119251-A1 AGRICULTURAL PLANT-PROTECTING AGENTS CONTAINING DIPEPTIDE DERIVATIVE AS ACTIVE INGREDIENT PEPD, DNPEP, DPP7 CA12 2957/4885CA14 2092/4885KMT2A 1691/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.