SCHEMBL29918031

SCHEMBL29918031

C[C@H](NC(=O)OC(C)(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)OC(C)(C)C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.47
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CTSK P43235 5/20 0.43
CTSS P25774 4/20 0.43
CA12 O43570 1/20 0.42
CA14 Q9ULX7 1/20 0.42
GLA P06280 2/20 0.42
MAPT P10636 2/20 0.42
KDM4E B2RXH2 1/20 0.42
GAA P10253 1/20 0.42
HPGD P15428 1/20 0.42
GLS O94925 1/20 0.42
CYP2D6 P10635 1/20 0.41
CTSL P07711 1/20 0.41
CTSB P07858 1/20 0.41
NPSR1 Q6W5P4 2/20 0.41
EPHX2 P34913 1/20 0.40
RECQL P46063 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29918107 1.00 KMT2A (0.47) KMT2ACA1CA2CA7CTSK
SCHEMBL23607312 0.92 CA1 (0.52) KMT2ACA1CA2CA7CTSK
SCHEMBL1689249 0.92 CA1 (0.52) KMT2ACA1CA2CA7CTSK
SCHEMBL23849248 0.92 CA1 (0.52) KMT2ACA1CA2CA7CTSK
SCHEMBL30134977 0.91 CA12 (0.53) KMT2ACA1CA2CA7CTSK
SCHEMBL21737876 0.91 CA12 (0.53) KMT2ACA1CA2CA7CTSK
SCHEMBL26030105 0.91 CA12 (0.53) KMT2ACA1CA2CA7CTSK
SCHEMBL16667828 0.91 CA12 (0.53) KMT2ACA1CA2CA7CTSK
SCHEMBL13112912 0.91 CA12 (0.53) KMT2ACA1CA2CA7CTSK
SCHEMBL9137141 0.91 CA12 (0.53) KMT2ACA1CA2CA7CTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240209020-A1 REACTION AGENT FOR AMIDE REACTION AND METHOD FOR PRODUCING AMIDE COMPOUND USING SAME CHUBU UNIVERSITY EDUCATIONAL FOUNDATION (JP) 2024-06-27 US disclosed
EP-4357353-A1 PEPTIDE COMPOUND PRODUCTION METHOD Chubu University Educational Foundation (JP) 2024-04-24 EP disclosed
EP-3786151-B1 METHOD FOR PRODUCING AMIDE COMPOUND CHUBU UNIV EDUCATIONAL FOUNDATION (JP) 2023-06-07 EP disclosed
CN-112020492-B Method for producing amide compound 学校法人中部大学 2023-05-05 CN disclosed
US-20230121469-A1 CATALYST FOR MANUFACTURING AMIDE COMPOUND, AND METHOD FOR MANUFACTURING AMIDE COMPOUND CHUBU UNIVERSITY EDUCATIONAL FOUNDATION (JP) 2023-04-20 US disclosed
WO-2022265115-A1 PEPTIDE COMPOUND PRODUCTION METHOD 学校法人中部大学 2022-12-22 WO disclosed
US-11512108-B2 Method for producing amide compound CHUBU UNIVERSITY EDUCATIONAL FOUNDATION (JP) 2022-11-29 US disclosed
EP-4053101-A1 REACTION AGENT FOR AMIDE REACTION AND METHOD FOR PRODUCING AMIDE COMPOUND USING SAME Chubu University Educational Foundation (JP) 2022-09-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230121469-A1 CATALYST FOR MANUFACTURING AMIDE COMPOUND, AND METHOD FOR MANUFACTURING AMIDE COMPOUND NAAA, ASNS, BCAT2 KMT2A 866/4885CA1 466/4885CA2 1388/4885
US-20240209020-A1 REACTION AGENT FOR AMIDE REACTION AND METHOD FOR PRODUCING AMIDE COMPOUND USING SAME NAAA, FAAH, FAAH2 KMT2A 1120/4885CA1 136/4885CA2 1234/4885
US-11512108-B2 Method for producing amide compound BCAT2, ASNS, VIP KMT2A 1202/4885CA1 62/4885CA2 1151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.