SCHEMBL16668153

SCHEMBL16668153

O=C1C=C(CCCCCC2=CC(=O)NC2=O)C(=O)N1.O=C1C=CC(=O)N1

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GSK3A P49840 1/20 0.44
GSK3B P49841 1/20 0.44
CCR6 P51684 1/20 0.44
ACHE P22303 1/20 0.35
BACE1 P56817 1/20 0.35
STAT3 P40763 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29395797 0.92 STAT3 (0.39) ACHEBACE1STAT3
SCHEMBL549066 0.92 STAT3 (0.39) ACHEBACE1STAT3
SCHEMBL586641 0.92 STAT3 (0.39) ACHEBACE1STAT3
SCHEMBL10428730 0.92 STAT3 (0.39) ACHEBACE1STAT3
SCHEMBL549041 0.92 STAT3 (0.39) ACHEBACE1STAT3
SCHEMBL6910095 0.92 STAT3 (0.39) ACHEBACE1STAT3
SCHEMBL548131 0.92 STAT3 (0.39) ACHEBACE1STAT3
SCHEMBL10428620 0.92 STAT3 (0.39) ACHEBACE1STAT3
SCHEMBL10626678 0.91 GSK3A (0.37) GSK3AGSK3BCCR6ACHEBACE1
SCHEMBL1726622 0.91 ACHE (0.49) GSK3AGSK3BCCR6ACHEBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10011751-B2 Phosphine-catalyzed, michael addition-curable sulfur-containing polymer compositions PRC-DESOTO INTERNATIONAL, INC. (US) 2018-07-03 US claimed
CN-117186766-A Catalytic composition and thiol-ene based composition with extended pot life PPG工业俄亥俄公司 2023-12-08 CN disclosed
CN-113227213-B Catalytic composition and thiol-ene based composition with extended pot life PPG工业俄亥俄公司 2023-09-05 CN disclosed
US-11628431-B2 Catalytic compositions and thiolene-based compositions with extended pot life PPG INDUSTRIES OHIO, INC. (US) 2023-04-18 US disclosed
EP-3445499-B1 IONIC LIQUID CATALYST IN SULFUR-CONTAINING POLYMER COMPOSITIONS PRC DESOTO INT INC (US) 2022-06-08 EP disclosed
CN-113227213-A Catalytic composition and thiol-ene-based composition with extended pot life PPG工业俄亥俄公司 2021-08-06 CN disclosed
US-20210170382-A1 CATALYTIC COMPOSITIONS AND THIOLENE-BASED COMPOSITIONS WITH EXTENDED POT LIFE PPG INDUSTRIES OHIO, INC. (US) 2021-06-10 US disclosed
US-10981158-B2 Catalytic compositions and thiolene-based compositions with extended pot life PPG INDUSTRIES OHIO, INC. (US) 2021-04-20 US disclosed
CN-108350119-B Catalytic composition and thiol-ene based composition with extended pot life PPG工业俄亥俄公司 2021-04-20 CN disclosed
EP-3750926-A1 CATALYTIC COMPOSITIONS AND THIOLENE-BASED COMPOSITIONS WITH EXTENDED POT LIFE PPG Industries Ohio, Inc. (US) 2020-12-16 EP disclosed
US-9611359-B2 Maleimide-terminated sulfur-containing polymers, compositions thereof, and uses thereof PRC-DESOTO INTERNATIONAL, INC. (US) 2017-04-04 US disclosed
EP-3114155-A1 PHOSPHINE-CATALYZED, MICHAEL ADDITION-CURABLE SULFUR-CONTAINING POLYMER COMPOSITIONS PRC-Desoto International, Inc. (US) 2017-01-11 EP disclosed
US-20160264697-A1 CATALYTIC COMPOSITIONS AND THIOLENE-BASED COMPOSITIONS WITH EXTENDED POT LIFE PPG INDUSTRIES OHIO, INC. 2016-09-15 US disclosed
EP-3063207-A2 MALEIMIDE-TERMINATED SULFUR-CONTAINING POLYMERS, COMPOSITIONS THEREOF, AND USES THEREOF PRC-Desoto International, Inc. (US) 2016-09-07 EP disclosed
US-20160186025-A1 PHOSPHINE-CATALYZED, MICHAEL ADDITION-CURABLE SULFUR-CONTAINING POLYMER COMPOSITIONS PRC DESOTO INT INC (US) 2016-06-30 US disclosed
US-9328275-B2 Phosphine-catalyzed, michael addition-curable sulfur-containing polymer compositions PRC DESOTO INTERNATIONAL, INC. (US) 2016-05-03 US disclosed
WO-2015134843-A1 PHOSPHINE-CATALYZED, MICHAEL ADDITION-CURABLE SULFUR-CONTAINING POLYMER COMPOSITIONS PRC-DESOTO INTERNATIONAL, INC. (US) 2015-09-11 WO disclosed
US-20150252233-A1 PHOSPHINE-CATALYZED. MICHAEL ADDITION-CURABLE SULFUR-CONTAINING POLYMER COMPOSITIONS PRC-DESOTO INTERNATIONAL, INC. (US) 2015-09-10 US disclosed
WO-2015066192-A2 MALEIMIDE-TERMINATED SULFUR-CONTAINING POLYMERS, COMPOSITIONS THEREOF, AND USES THEREOF PRC-DESOTO INTERNATIONAL, INC. (US) 2015-05-07 WO disclosed
US-20150119549-A1 MALEIMIDE-TERMINATED SULFUR-CONTAINING POLYMERS, COMPOSITIONS THEREOF, AND USES THEREOF PRC-DESOTO INTERNATIONAL, INC. (US) 2015-04-30 US disclosed