⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12988591 | 0.67 | — | — | |
| SCHEMBL1703286 | 0.67 | — | — | |
| SCHEMBL16962742 | 0.67 | CNR2 (0.37) | — | |
| SCHEMBL15230001 | 0.64 | — | — | |
| SCHEMBL13967138 | 0.62 | ALDH1A1 (0.35) | — | |
| SCHEMBL8419432 | 0.59 | — | — | |
| SCHEMBL16180715 | 0.56 | SRC (0.34) | — | |
| SCHEMBL22445250 | 0.54 | — | — | |
| SCHEMBL14230689 | 0.52 | ALDH1A1 (0.41) | — | |
| SCHEMBL31708221 | 0.51 | ALDH1A1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2308870-A2 | 2-oxo-1-pyrrolidine deriatives, processes for preparing them and their uses | UCB Pharma S.A. (BE) | 2011-04-13 | — | — | EP | disclosed |