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Uridine Triphosphate

Uridine Triphosphate

SCHEMBL166686

O=C(O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21.O=c1ccn([C@@H]2O[C@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]2O)c(=O)[nH]1

nearest known ligand 0.61

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Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ P2RY2 P41231 15/20 0.61
▸ P2RY4 P51582 9/20 0.61
▸ P2RY6 Q15077 7/20 0.61
▸ P2RY14 Q15391 4/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biotin SCHEMBL381578 0.90 DUT (0.52) P2RY2P2RY4P2RY6
SCHEMBL14204816 0.85 P2RY2 (0.54) P2RY2P2RY4P2RY6P2RY14
SCHEMBL14204819 0.85 P2RY6 (0.54) P2RY2P2RY4P2RY6P2RY14
SCHEMBL523981 0.83 F2 (0.47) P2RY2P2RY4P2RY6
Uridine Triphosphate SCHEMBL24414746 0.81 P2RY2 (0.94) P2RY2P2RY4P2RY6P2RY14
Uridine Triphosphate SCHEMBL2778525 0.81 P2RY2 (0.94) P2RY2P2RY4P2RY6P2RY14
SCHEMBL376210 0.81 P2RY2 (0.94) P2RY2P2RY4P2RY6P2RY14
Uridine Triphosphate SCHEMBL14406726 0.81 P2RY2 (0.94) P2RY2P2RY4P2RY6P2RY14
Uridine Triphosphate SCHEMBL12671699 0.81 P2RY2 (0.94) P2RY2P2RY4P2RY6P2RY14
Uridine Triphosphate SCHEMBL76682 0.81 P2RY2 (0.94) P2RY2P2RY4P2RY6P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160015743-A1 METHODS FOR TREATING CANCER RUSH UNIVERSITY MEDICAL CENTER (US) 2016-01-21 — — US disclosed
US-9102942-B2 Pharmaceutical composition for inhibiting abnormal proliferation of cells EWHA University—Industry Collaboration Foundation (KR) 2015-08-11 — — US disclosed
US-20120308568-A1 PHARMACEUTICAL COMPOSITION FOR INHIBITING ABNORMAL PROLIFERATION OF CELLS EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION (KR) 2012-12-06 — — US disclosed
WO-2011096756-A9 PHARMACEUTICAL COMPOSITION FOR INHIBITING ABNORMAL PROLIFERATION OF CELLS 이화여자대학교 산학협력단 (KR) 2012-03-08 — — WO disclosed
WO-2011096756-A2 PHARMACEUTICAL COMPOSITION FOR INHIBITING ABNORMAL PROLIFERATION OF CELLS 이화여자대학교 산학협력단 (KR) 2011-08-11 — — WO disclosed