Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.55 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.50 |
| ▸ | THRA | P10827 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16676908 | 1.00 | TSHR (0.65) | TSHRPLA2G4BSMPD1LTA4HGPBAR1 | |
| SCHEMBL14566074 | 0.94 | HRH3 (0.59) | TSHRPLA2G4BSMPD1HRH3ALDH1A1 | |
| SCHEMBL14566089 | 0.94 | HRH3 (0.59) | TSHRPLA2G4BSMPD1HRH3ALDH1A1 | |
| SCHEMBL14566086 | 0.94 | HRH3 (0.59) | TSHRPLA2G4BSMPD1HRH3ALDH1A1 | |
| SCHEMBL14566088 | 0.94 | HRH3 (0.59) | TSHRPLA2G4BSMPD1HRH3ALDH1A1 | |
| SCHEMBL16667638 | 0.93 | TSHR (0.54) | TSHRPLA2G4BLTA4HGPBAR1HRH3 | |
| SCHEMBL16676014 | 0.93 | TSHR (0.54) | TSHRPLA2G4BLTA4HGPBAR1HRH3 | |
| SCHEMBL3905859 | 0.91 | TSHR (0.76) | TSHRPLA2G4BSMPD1LTA4HGPBAR1 | |
| SCHEMBL4208924 | 0.91 | TSHR (0.76) | TSHRPLA2G4BSMPD1LTA4HGPBAR1 | |
| SCHEMBL6677146 | 0.91 | TSHR (0.76) | TSHRPLA2G4BSMPD1LTA4HGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10323204-B2 | Low viscosity, low volatility lubricating oil basestocks | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2019-06-18 | — | — | US | disclosed |
| US-20150119307-A1 | LOW VISCOSITY, LOW VOLATILITY LUBRICATING OIL BASESTOCKS | EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) | 2015-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10323204-B2 | Low viscosity, low volatility lubricating oil basestocks | TYK2, JAK1, CEL | TSHR 2977/4885PLA2G4B 542/4885SMPD1 2651/4885 |
| US-20150119307-A1 | LOW VISCOSITY, LOW VOLATILITY LUBRICATING OIL BASESTOCKS | TYK2, JAK1, CEL | TSHR 2977/4885PLA2G4B 542/4885SMPD1 2651/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.