Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 3/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 12/20 | 0.46 |
| ▸ | ESR1 | P03372 | 11/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | BCR | P11274 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18184906 | 0.87 | PDK2 (0.52) | PDK2ESR2ESR1KDM4EMEN1 | |
| SCHEMBL25026531 | 0.87 | ESR2 (0.49) | PDK2ESR2ESR1CYP1A2CYP3A4 | |
| SCHEMBL26250566 | 0.86 | ESR2 (0.56) | PDK2ESR2ESR1CYP1A2CYP3A4 | |
| SCHEMBL14506088 | 0.86 | ESR2 (0.56) | PDK2ESR2ESR1CYP1A2CYP3A4 | |
| SCHEMBL16176940 | 0.86 | PDK2 (0.55) | PDK2ESR2ESR1KDM4EMEN1 | |
| SCHEMBL29615782 | 0.86 | PDK2 (0.55) | PDK2ESR2ESR1KDM4EMEN1 | |
| SCHEMBL29375118 | 0.86 | PDK2 (0.55) | PDK2ESR2ESR1KDM4EMEN1 | |
| SCHEMBL29756627 | 0.86 | PDK2 (0.55) | PDK2ESR2ESR1KDM4EMEN1 | |
| SCHEMBL16177483 | 0.86 | PDK2 (0.55) | PDK2ESR2ESR1KDM4EMEN1 | |
| SCHEMBL29493741 | 0.86 | PDK2 (0.55) | PDK2ESR2ESR1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9876174-B2 | Electronic device including a fluoranthene derivative | E I DU PONT DE NEMOURS AND COMPANY (US) | 2018-01-23 | — | — | US | disclosed |
| US-9876174-B2 | Electronic device including a fluoranthene derivative | E I DU PONT DE NEMOURS AND COMPANY (US) | 2018-01-23 | — | — | US | disclosed |
| US-9876174-B2 | Electronic device including a fluoranthene derivative | E I DU PONT DE NEMOURS AND COMPANY (US) | 2018-01-23 | — | — | US | disclosed |
| US-9716233-B2 | Electronic device including a fluoranthene derivative | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-07-25 | — | — | US | disclosed |
| US-9716233-B2 | Electronic device including a fluoranthene derivative | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-07-25 | — | — | US | disclosed |
| US-9716233-B2 | Electronic device including a fluoranthene derivative | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-07-25 | — | — | US | disclosed |
| US-20170200900-A1 | ELECTRONIC DEVICE INCLUDING A FLUORANTHENE DERIVATIVE | LG CHEM, LTD. (KR) | 2017-07-13 | — | — | US | disclosed |
| US-20170200900-A1 | ELECTRONIC DEVICE INCLUDING A FLUORANTHENE DERIVATIVE | LG CHEM, LTD. (KR) | 2017-07-13 | — | — | US | disclosed |
| US-20170200900-A1 | ELECTRONIC DEVICE INCLUDING A FLUORANTHENE DERIVATIVE | LG CHEM, LTD. (KR) | 2017-07-13 | — | — | US | disclosed |
| US-20160268514-A1 | ELECTRONIC DEVICE INCLUDING A FLUORANTHENE DERIVATIVE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2016-09-15 | — | — | US | disclosed |
| US-20160268514-A1 | ELECTRONIC DEVICE INCLUDING A FLUORANTHENE DERIVATIVE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2016-09-15 | — | — | US | disclosed |
| US-20160268514-A1 | ELECTRONIC DEVICE INCLUDING A FLUORANTHENE DERIVATIVE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2016-09-15 | — | — | US | disclosed |
| WO-2015061074-A1 | ELECTRONIC DEVICE INCLUDING A FLUORANTHENE DERIVATIVE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2015-04-30 | — | — | WO | disclosed |
| WO-2015061074-A1 | ELECTRONIC DEVICE INCLUDING A FLUORANTHENE DERIVATIVE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2015-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160268514-A1 | ELECTRONIC DEVICE INCLUDING A FLUORANTHENE DERIVATIVE | NR0B1, AR, NR0B2 | PDK2 3733/4885ESR2 16/4885ESR1 20/4885 |
| US-20170200900-A1 | ELECTRONIC DEVICE INCLUDING A FLUORANTHENE DERIVATIVE | AR, CCND3, ESRRA | PDK2 3652/4885ESR2 13/4885ESR1 17/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.