Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.58 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.45 |
| ▸ | ANPEP | P15144 | 6/20 | 0.39 |
| ▸ | RNPEP | Q9H4A4 | 4/20 | 0.39 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.38 |
| ▸ | LAP3 | P28838 | 5/20 | 0.37 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.36 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16062283 | 1.00 | SLC7A5 (0.58) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| SCHEMBL995721 | 0.89 | SLC7A5 (0.58) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| SCHEMBL9100153 | 0.89 | SLC7A5 (0.58) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| SCHEMBL7676359 | 0.83 | SLC7A5 (0.52) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| SCHEMBL998946 | 0.83 | SLC7A5 (0.52) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| SCHEMBL1585736 | 0.83 | SLC7A5 (0.52) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| SCHEMBL29269090 | 0.83 | SLC7A5 (0.52) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| SCHEMBL541251 | 0.83 | SLC7A5 (0.52) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| SCHEMBL7361839 | 0.83 | SLC7A5 (0.52) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP | |
| SCHEMBL14485413 | 0.83 | SLC7A5 (0.52) | SLC7A5SLC1A3SLC1A2ANPEPRNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170027897-A1 | mTORC1 MODULATION BY AMINO ACIDS AND USES THEREOF | WHITEHEAD INST BIOMEDICAL RES (US) | 2017-02-02 | — | — | US | disclosed |
| EP-3060231-A1 | MTORC1 MODULATION BY AMINO ACIDS AND USES THEREOF | The Whitehead Institute for Biomedical Research (US) | 2016-08-31 | — | — | EP | disclosed |
| WO-2015061607-A1 | MTORC1 MODULATION BY AMINO ACIDS AND USES THEREOF | WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2015-04-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170027897-A1 | mTORC1 MODULATION BY AMINO ACIDS AND USES THEREOF | MTOR, RPTOR, EIF4EBP1 | SLC7A5 1686/4885SLC1A3 834/4885SLC1A2 1142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.