SCHEMBL541251

SCHEMBL541251

CC(=O)OC(=O)[C@@H](N)CC(C)C

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ SLC7A5 Q01650 1/20 0.52
▸ SLC1A3 P43003 3/20 0.41
▸ SLC1A2 P43004 3/20 0.41
▸ ANPEP P15144 7/20 0.39
▸ RNPEP Q9H4A4 3/20 0.39
▸ DNPEP Q9ULA0 2/20 0.39
▸ TSHR P16473 3/20 0.38
▸ ALDH1A1 P00352 2/20 0.38
▸ LAP3 P28838 4/20 0.35
▸ ERAP1 Q9NZ08 1/20 0.35
▸ MAPK1 P28482 1/20 0.35
▸ SLC1A1 P43005 2/20 0.34
▸ LARS1 Q9P2J5 1/20 0.33
▸ DPP4 P27487 1/20 0.33
▸ DPP8 Q6V1X1 1/20 0.33
▸ DPP9 Q86TI2 1/20 0.33
▸ DPP7 Q9UHL4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9100153 0.89 SLC7A5 (0.58) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL995721 0.89 SLC7A5 (0.58) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL8517612 0.85 ALDH1A1 (0.36) SLC7A5SLC1A3SLC1A2TSHRALDH1A1
SCHEMBL28742569 0.83 SLC7A5 (0.48) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL1585736 0.83 SLC7A5 (0.52) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL16062283 0.83 SLC7A5 (0.58) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL998946 0.83 SLC7A5 (0.52) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL16670559 0.83 SLC7A5 (0.58) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL7676359 0.83 SLC7A5 (0.52) SLC7A5SLC1A3SLC1A2ANPEPRNPEP
SCHEMBL7361839 0.83 SLC7A5 (0.52) SLC7A5SLC1A3SLC1A2ANPEPRNPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3752141-B1 ACETYL-LEUCINE FOR USE IN TREATING RESTLESS LEG SYNDROME INTRABIO LTD (GB) 2024-06-05 — — EP claimed
WO-2024079733-A1 PROCESS FOR THE PREPARATION OF AMINOPYRIDAZINE DERIVATIVES ADAMA MAKHTESHIM LTD. (IL) 2024-04-18 — — WO claimed
US-11793817-B2 Muscarinic M1 receptor agonists HEPTARES THERAPEUTICS LIMITED (GB) 2023-10-24 — — US claimed
US-20210353637-A1 MUSCARINIC M1 RECEPTOR AGONISTS NXERA PHARMA UK LIMITED (GB) 2021-11-18 — — US claimed
EP-3638370-B1 TREATMENT OF MIGRAINE WITH ACETYL-LEUCINE INTRABIO LTD (GB) 2020-11-11 — — EP claimed
CN-110818620-A Preparation method of meta-aromatic aldehyde 安阳师范学院 2020-02-21 — — CN claimed
US-20190160027-A1 SALBUTAMOL-CONTAINING OPHTHALMIC MEDICAMENT REKIK RAOUF (TN) 2019-05-30 — — US claimed
EP-3416631-B1 THERAPEUTIC AGENTS FOR NEURODEGENERATIVE DISEASES INTRABIO LTD (GB) 2019-05-15 — — EP claimed
EP-3257910-B1 CHEMICAL MECHANICAL POLISHING (CMP) COMPOSITION, METHOD AND SYSTEM FOR COBALT-CONTAINING SUBSTRATE VERSUM MAT US LLC (US) 2019-03-27 — — EP claimed
EP-3359146-B1 PHARMACEUTICAL COMPOSITIONS AND USES DIRECTED TO LYSOSOMAL STORAGE DISORDERS INTRABIO LTD (GB) 2019-01-23 — — EP claimed
EP-1571986-A2 MANAGEMENT OF GASTRO-INTESTINAL DISORDERS Oridion Breathid Ltd. (IL) 2005-09-14 — — EP claimed
US-20050020931-A1 Management of gastro-intestinal disorders ORIDION BREATHID LTD. (IL) 2005-01-27 — — US claimed
EP-1427325-A2 MANAGEMENT OF GASTRO-INTESTINAL DISORDERS Oridion Breathid Ltd. (IL) 2004-06-16 — — EP claimed
WO-2004002307-A2 MANAGEMENT OF GASTRO-INTESTINAL DISORDERS ORIDION BREATHID LTD. (IL) 2004-01-08 — — WO claimed
WO-2004002308-A2 MANAGEMENT OF GASTRO-INTESTINAL DISORDERS ORIDION BREATHID LTD. (IL) 2004-01-08 — — WO claimed
EP-1006997-B1 EFFERVESCENT MICROSPHERES AND METHOD FOR MAKING THEM PF MEDICAMENT (FR) 2003-07-02 — — EP claimed
WO-2003017818-A2 MANAGEMENT OF GASTRO-INTESTINAL DISORDERS ORIDION BREATHID LTD. (IL) 2003-03-06 — — WO claimed
US-5519000-A OLIGOPEPTIDE CENTECOR, INC. (US) 1996-05-21 — — US claimed
WO-1995026744-A1 TUMOR NECROSIS FACTOR INHIBITORS CENTOCOR, INC. (US) 1995-10-12 — — WO claimed
CN-1091952-A Cosmetic composition UNILEVER NV (NL) 1994-09-14 — — CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190160027-A1 SALBUTAMOL-CONTAINING OPHTHALMIC MEDICAMENT ADRB3, ADRB2, ADRB1 SLC7A5 3602/4885SLC1A3 3140/4885SLC1A2 2077/4885
US-20210353637-A1 MUSCARINIC M1 RECEPTOR AGONISTS CHRM1, CHRM2, CHRM3 SLC7A5 3637/4885SLC1A3 1289/4885SLC1A2 801/4885
US-11793817-B2 Muscarinic M1 receptor agonists CHRM1, CHRM2, CHRM3 SLC7A5 3637/4885SLC1A3 1289/4885SLC1A2 801/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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